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Transcription and translation (TX-TL) can be performed in vitro, outside of cells, allowing the assembly and analysis of genetic networks. This approach to engineering biological networks in a less complex and more controllable environment could one day al ...
Benzothiazinones (BTZ) are a new class of drug candidates to combat tuberculosis that inhibit decaprenyl-phosphoribose epimerase (DprE1), an essential enzyme involved in arabinan biosynthesis. Using the checkerboard method and cell viability assays, we hav ...
Microbial Induced Calcite Precipitation (MICP) is an innovative technique for soil grouting in which injected bacteria supplemented with chemicals lead to calcite precipitation in soils. A comprehensive research work is carried out to better understand and ...
A wide variety of antibacterial compounds is rapidly oxidized by O-3 and hydroxyl radical ((OH)-O-center dot) during aqueous ozonation. Quantitative microbiological assays have been developed here or adapted from existing methods and utilized to measure th ...
To locate a high-dose point hexachlorocyclohexane (HCH)-contaminated site, to identify HCH-degrading bacteria in it and assay HCH-decontamination by biostimulation. Methods and Results: Bacteria were isolated by serial dilution method from HCH-contaminate ...
The Mycobacterium tuberculosis genome encodes for eleven eukaryotic-like Ser/Thr protein kinases. At least three of these (PknA, PknB and PknG) are essential for bacterial growth and survival. PknG is secreted by pathogenic mycobacteria, in macrophages to ...
Several pathogens - bacteria, viruses and parasites - must enter mammalian cells for survival, replication and immune-system evasion. These pathogens generally make use of existing cellular pathways that are designed for nutrient uptake, receptor downregul ...
