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Complex events are instrumental in understanding advanced behaviours and properties of a system. They can represent more meaningful events as compared to simple events. In this thesis we propose to use wearable sensor signals to detect complex events. Thes ...
An increasing number of industrial bioprocesses capitalize on living cells by using them as cell factories that convert sugars into chemicals. These processes range from the production of bulk chemicals in yeasts and bacteria to the synthesis of therapeuti ...
Here we report that gamma-valerolactone (GVL), a biomass-derived solvent, can be used to facilitate the mild pretreatment of lignocellulosic biomass. An 80% GVL, 20% water solvent system was used to pretreat hardwood at the mild temperature of 120 degrees ...
Lactic acid (LA) is considered for the diversification and value addition to sugar industry in South Africa, through a bioconversion of sugarcane bagasse and leaves. A bioconversion process was modeled in Aspen Plus (R) V8.6 and its environmental impacts w ...
The condensational growth of a water droplet follows water vapor accommodation and is described by the mass accommodation coefficient, a. To determine a for droplets coated by straight chain and branched alcohols, we perform molecular dynamics simulations ...
Background: The control of the functional pancreatic beta-cell mass serves the key homeostatic function of releasing the right amount of insulin to keep blood sugar in the normal range. It is not fully understood though how beta-cell mass is determined. ...
Electron microscopy (EM) entered a new era with the emergence of direct electron detectors and new nanocrystal electron diffraction methods. However, sample preparation techniques have not progressed and still suffer from extensive blotting steps leading t ...
Biomolecular functional complexes often serve as inspiration for the development of artificial molecular nanostructures. The functionality of the biomolecular structures is based on complex and adaptable binding motifs that have evolved over billions of ye ...
Vicinal amino alcohols are important structural motifs of bioactive compounds. Reported herein is an efficient method for their synthesis based on the palladium-catalyzed oxy-alkynylation, oxy-arylation, or oxy-vinylation of allylic amines. High regio- and ...
We present herein a thorough description of the effects of high glucose concentrations on the diffusion, hydration and internal dynamics of ubiquitin, as predicted from extensive molecular dynamics simulations on several systems described at fully atomisti ...