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It is well established that lactate can be used as an energy substrate by the brain by conversion to pyruvate and a subsequent oxidation in the mitochondria. Knowing the need for readily metabolizable substrates directly after ischemia and the protective e ...
Nicotinic acetylcholine receptors are heteropentameric ion channels that open upon activation to a single conducting state. The second transmembrane segments of each subunit were identified as channel-forming elements, but their respective contribution in ...
A method for labeling acyl carrier protein (ACP) fusion proteins using derivs. of CoA is described. The method relies on the transfer of a label from a CoA type substrate to an ACP fusion protein using a holo-acyl carrier protein synthase (ACPS) or a homol ...
(EPFL-Ecole Polytechnique Federale de Lausanne, Switz.).2004
A symposium report on the construction of regioselectively addressable functionalized template (RAFT) mols., e.g. I [R = Me3CO2C (Boc); R1 = H2C:CHCH2O2C (Alloc)], as conformationally stable cyclopeptide scaffolds in which lysine side chains point to oppos ...
The long-chain acyl-coenzyme A synthetase (ACS) gene gives rise to three transcripts containing different first exons preceded by specific regulatory regions A, B, and C. Exon-specific oligonucleotide hybridization indicated that only A-ACS mRNA is express ...
We have determined the frequency of the A985G mutation in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in a cohort of 1142 healthy babies born in two Geneva hospitals. Among babies with at least one Swiss parent, heterozygotes were detected at a fre ...
Monomolecular layers of lipid extracts of microsomal, mitochondrial outer and inner membranes, and pure lipid species have been used to measure their interaction with apo- and holocytochrome c. Large differences were observed both with respect to the natur ...
American Society for Biochemistry and Molecular Biology1989
