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Visual comfort at workplaces has often been considered in terms of discomfort glare, luminance distribution and task visibility. Besides visual effects, the lighting environment has also impact on human physiology and behaviour. These effects of light are ...
Endogenous rhythms of circalunar periodicity (similar to 29.5 days) and their underlying molecular and genetic basis have been demonstrated in a number of marine species [1, 2]. In contrast, there is a great deal of folklore but no consistent association o ...
Lighting is one of the most significant factors in the built environment that affect human health and wellbeing. In addition to stimulating visual responses, light induces a range of non-visual responses in humans including synchronizing circadian rhythms ...
Age-related disturbances of the sleep-wake cycle can reflect ontogenetic changes in regulatory mechanisms underlying normal and pathological aging, but the exact nature of these changes remains unclear. The present report is the first attempt to apply prin ...
Sleep fragmentation is present in numerous sleep pathologies and constitutes a major feature of patients with obstructive sleep apnea. A prevalence of metabolic syndrome, diabetes and obesity has been shown to be associated to obstructive sleep apnea. Whil ...
A new wall shear stress model to be used as a wall boundary condition for large-eddy simulations of the atmospheric boundary layer is proposed. The new model computes the wall shear stress and the vertical derivatives of the streamwise velocity component b ...
The constant amplitude fatigue behavior of adhesively bonded pultruded glass fiber reinforced polymer double-lap joints were modeled by a number of conceptually different phenomenological SN (cyclic stress vs. number of cycle) formulations. An extended dat ...
Environmental light synchronizes the primary mammalian biological clock in the suprachiasmatic nuclei, as well as many peripheral clocks in tissues and cells, to the solar 24-hour day. Light is the strongest synchronizing agent (zeitgeber) for the circadia ...
In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus constitutes the central circadian pacemaker. The SCN receives light signals from the retina and controls peripheral circadian clocks (located in the cortex, the pineal gland, the liver, the ...
Epigenetic regulation of gene expression is strongly influenced by the accessibility of nucleosomal DNA or the state of chromatin compaction. In this context, coregulators, including both coactivators and corepressors, are pivotal intermediates that bridge ...