Concept
Circulatory system
Related publications (293)
Re-evaluating the mythical divide between traditional and novel cardiovascular risk factors in rheumatoid arthritis
Cardiovascular (CV) risk factors for rheumatoid arthritis (RA) are conventionally classified as 'traditional' and 'novel'. We argue that this classification is obsolete and potentially counterproductive. Further, we discuss problems with the common practic ...
London2024The role of computational methods in cardiovascular medicine: a narrative review
Alfio Quarteroni, Luca Dede', Christian Vergara, Stefano Pagani
Background and Objective: Computational models of the cardiovascular system allow for a detailed and quantitative investigation of both physiological and pathological conditions, thanks to their ability to combine clinical-possibly patient-specific-data wi ...
Ame Publishing Company2024The Impact of Left Ventricular Performance and Afterload on the Evaluation of Aortic Valve Stenosis: A 1D Mathematical Modeling Approach
The transaortic valvular pressure gradient (TPG) plays a central role in decision-making for patients suffering from severe aortic stenosis. However, the flow-dependence nature of the TPG makes the diagnosis of aortic stenosis challenging since the markers ...
MDPI2023Design and computational optimization of compliance-matching aortic grafts
Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia
Introduction: Synthetic vascular grafts have been widely used in clinical practice for aortic replacement surgery. Despite their high rates of surgical success, they remain significantly less compliant than the native aorta, resulting in a phenomenon calle ...
FRONTIERS MEDIA SA2023Modulation of Pulsatile Left Ventricular Afterload by Renal Denervation in Heart Failure With Preserved Ejection Fraction
Nikolaos Stergiopoulos, Stamatia Zoi Pagoulatou
Background:Arterial stiffening contributes to hemodynamic derangements in heart failure with preserved ejection fraction (HFpEF). We sought to investigate the impact of renal denervation on pulsatile left ventricular loading in patients with HFpEF and hype ...
Philadelphia2023A Comparison of Residual-based Methods on Fault Detection
Olga Fink, Gaëtan Michel Frusque
An important initial step in fault detection for complex industrial systems is gaining an understanding of their health condition. Subsequently, continuous monitoring of this health condition becomes crucial to observe its evolution, track changes over tim ...
PHM Society2023Cardiac output estimated from an uncalibrated radial blood pressure waveform: validation in an in-silico-generated population
Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia
Background: Cardiac output is essential for patient management in critically ill patients. The state-of-the-art for cardiac output monitoring bears limitations that pertain to the invasive nature of the method, high costs, and associated complications. Hen ...
FRONTIERS MEDIA SA2023Sporadic type VI secretion in seventh pandemic Vibrio cholerae
Melanie Blokesch, Sandrine Stutzmann, Nicolas René Chiaruttini, Alexis Joseph Proutière, Loriane Bader, Lisa Christina Metzger, Natalia Carolina Drebes Dorr, Sandrine Natacha Isaac
Vibrio cholerae is a pathogen that causes disease in millions of people every year by colonizing the small intestine and then secreting the potent cholera toxin. How the pathogen overcomes the colonization barrier created by the host’s natural microbiota i ...
2023Validation of a Non-invasive Inverse Problem-Solving Method for Stroke Volume
Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou, Emma Marie Roussel
Stroke volume (SV) is a major biomarker of cardiac function, reflecting ventricular-vascular coupling. Despite this, hemodynamic monitoring and management seldomly includes assessments of SV and remains predominantly guided by brachial cuff blood pressure ...
FRONTIERS MEDIA SA2022Assessment of Stiffness of Large to Small Arteries in Multistage Renal Disease Model: A Numerical Study
Nikolaos Stergiopoulos, Vasiliki Bikia, Patrick Segers
Arterial stiffness (AS), as assessed via pulse wave velocity (PWV), is a major biomarker for cardiovascular risk assessment in patients with chronic kidney disease (CKD). However, the mechanisms responsible for the changes in PWV in the presence of kidney ...
FRONTIERS MEDIA SA2022