Publications related to Graft-versus-host disease

Selection of Vibrio crassostreae relies on a plasmid expressing a type 6 secretion system cytotoxic for host immune cells

Melanie Blokesch, Candice Stoudmann, Frédérique Marie Jeanne Le Roux

Pacific oyster mortality syndrome affects juveniles of Crassostrea gigas oysters and threatens the sustainability of commercial and natural stocks of this species. Vibrio crassostreae has been repeatedly isolated from diseased animals and the majority of t ...

2020

Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps

Arne Seitz, Romain Guiet, Nicola Harris, Beatrice Volpe, Tiffany Babette Angélique Bouchery, Kathleen Shah, Manuel Kulagin, Mati André Marie Moyat

Hookworms cause a major neglected tropical disease, occurring after larvae penetrate the host skin. Neutrophils are phagocytes that kill large pathogens by releasing neutrophil extracellular traps (NETs), but whether they target hookworms during skin infec ...

CELL PRESS2020

Structure and Function of the Branched Receptor-Binding Complex of Bacteriophage CBA120

Sergey Nazarov, Petr Leiman, Sergii Buth, Nikolai Prokhorov, Michel Plattner

Bacteriophages recognize their host cells with the help of tail fiber and tailspike proteins that bind, cleave, or modify certain structures on the cell surface. The spectrum of ligands to which the tail fibers and tailspikes can bind is the primary determ ...

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD2019

HIV Transmission Chains Exhibit Greater HLA-B Homogeneity Than Randomly Expected

Jacques Fellay, Christian Axel Wandall Thorball

Background: HIV's capacity to escape immune recognition by human leukocyte antigen (HLA) is a core component of HIV pathogenesis. A better understanding of the distribution of HLA class I in HIV-infected patients would improve our knowledge of pathogenesis ...

LIPPINCOTT WILLIAMS & WILKINS2019

Antibody‐mediated crosslinking of gut bacteria hinders the spread of antibiotic resistance

Anne-Florence Raphaëlle Bitbol, Loïc Marrec

The body is home to a diverse microbiota, mainly in the gut. Resistant bacteria are selected by antibiotic treatments, and once resistance becomes widespread in a population of hosts, antibiotics become useless. Here, we develop a multiscale model of the i ...

Wiley2019

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes

Nahal Mansouri, Sina Nassiri

Mesenchymal stromal/stem cell (MSC) therapy has shown promise in experimental models of idiopathic pulmonary fibrosis (IPF). The aim of this study was to test the therapeutic effects of extracellular vesicles produced by human BM MSCs (MEx) in a bleomycin- ...

AMER SOC CLINICAL INVESTIGATION INC2019

Fiber density of collagen grafts impacts rabbit urethral regeneration

Peter Frey, Jeffrey Alan Hubbell, Hans Mattias Larsson, Elif Vardar, Kalitha Pinnagoda, Ganesh Vythilingam

There is a need for efficient and “off-the-shelf” grafts in urethral reconstructive surgery. Currently available surgical techniques require harvesting of grafts from autologous sites, with increased risk of surgical complications and added patient discomf ...

2018

3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum

Henning Paul-Julius Stahlberg, Shyan Huey Low

Entry of the facultative intracellular pathogen Brucella into host cells results in the formation of endosomal Brucella-containing vacuoles (eBCVs) that initially traffic along the endocytic pathway. eBCV acidification triggers the expression of a type IV ...

The Company of Biologists2018

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Graft-versus-host disease

Selection of Vibrio crassostreae relies on a plasmid expressing a type 6 secretion system cytotoxic for host immune cells

Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps

Structure and Function of the Branched Receptor-Binding Complex of Bacteriophage CBA120

Weevil pgrp-lb prevents endosymbiont TCT dissemination and chronic host systemic immune activation

HIV Transmission Chains Exhibit Greater HLA-B Homogeneity Than Randomly Expected

Antibody‐mediated crosslinking of gut bacteria hinders the spread of antibiotic resistance

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes

Fiber density of collagen grafts impacts rabbit urethral regeneration

Development of functionalized alginate-based hydrogels to reduce fibrosis in the transplantation of microencapsulated cells

3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum

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HIV Transmission Chains Exhibit Greater HLA-B Homogeneity Than Randomly Expected

Weevil pgrp-lb prevents endosymbiont TCT dissemination and chronic host systemic immune activation

Selection of Vibrio crassostreae relies on a plasmid expressing a type 6 secretion system cytotoxic for host immune cells

Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps

Structure and Function of the Branched Receptor-Binding Complex of Bacteriophage CBA120

Antibody‐mediated crosslinking of gut bacteria hinders the spread of antibiotic resistance

Development of functionalized alginate-based hydrogels to reduce fibrosis in the transplantation of microencapsulated cells

Fiber density of collagen grafts impacts rabbit urethral regeneration

3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes