Concept

Bone density

Related publications (61)

3D model of bone remodeling coupled with a drug effect

Total hip replacement, which is a successful solution for restoring movement to damaged joints, becomes nowadays a common surgical procedure. However the lifespan of hip implants is limited, because of pathologic strain distribution in bone inducing bone-r ...

2009

A three-dimensional elastic plastic damage constitutive law for bone tissue

Alain Curnier

Motivated by mechanical analysis of bones and bone-implant systems, a 3D constitutive law describing the macroscopic mechanical behaviour of both cortical and trabecular bone in cyclic (not fatigue) overloads is developed. The proposed model which mathemat ...

Springer Verlag2009

Bone assessing method for fracture risk, involves inserting test probe through periosteum and soft tissue on bone of subject so that test probe contacts bone, where probe is inserted into bone to create microscopic fractures

Georg Fantner

NOVELTY - The method involves inserting a single use, replaceable test probe (800) through a periosteum and soft tissue on a bone of a subject so that the test probe contacts the subject`s bone. A material property of the bone is evaluated through the cont ...

Hansma P K; Rehn D J; Fantner G; Turner P J2008

Prevention of micromotion-related periprosthetic bone loss using local release of bisphosphonate

Vincent Stadelmann

Total joint replacements are highly successful in relieving pain and restoring movement of damaged joints. However, the lifespan of the implants is limited. The implant's long-term stability depends largely on the preservation of periprosthetic bone. Debri ...

EPFL2008

Investigation of the GK domain of PSD-95 in synaptic strength and structure

[...] Our findings show that a mutant of PSD-95 that lacks its GK domain clusters along the dendritic shaft and dramatically decreases the spine density without affecting the frequency of miniature excitatory postsynaptic currents (mEPSCs)[... click on "Do ...

2008

Bioluminescence imaging of calvarial bone repair using bone marrow and adipose tissue-derived mesenchymal stem cells

Jeffrey Alan Hubbell

A combined strategy using bioluminescence imaging, bone densitometry and histology was used to analyze the bone regeneration capacity of human bone marrow (hBMSC) and adipose tissue (hAMSC) mesenchymal stem cells, seeded in an osteoconductive arginine-glyc ...

2008

High-speed photography of compressed human trabecular bone correlates whitening to microscopic damage

Georg Fantner, Blake William Erickson

Mechanical testing of trabecular bone is mainly motivated by the huge impact of osteoporosis in post-menopausal women and the aged in society in terms of social and health care costs. Trabecular bone loss and impairment of its mechanical properties reduce ...

2007

Scanning and transmission electron microscopy for evaluation of order/disorder in bone structure

Philippe Buffat, Elena Suvorova Buffat

A comparative characterization of the structure of normal and abnormal (osteoporotic) human lumbar and thoracic vertebrae samples was carried out to reveal the type of possible disorder. Samples from the bone fragments extracted during the surgery due to v ...

2007

Nanoscale ion mediated networks in bone: Osteopontin can repeatedly dissipate large amounts of energy

Georg Fantner

In the nanocomposite bone, inorganic material is combined with several types of organic molecules, and these complexes have been proposed to increase the bone strength. Here we report on a mechanism of how one of these components, human osteopontin, forms ...

2007

Bone fracture risk assessing method involves inserting test probe through periosteum and soft tissue on bone, so as to evaluate resistance of bone to microscopic fracture

Georg Fantner

NOVELTY - The test probe (100) is inserted through periosteum and/or soft tissue on a bone, such that the test probe contacts the bone. The test probe is inserted multiple times into same location of the bone, to create one or more microscopic fractures in ...

2007

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