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Drug design

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Drug design

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Novel probes for the non-invasive bioluminescence imaging of mitochondrial membrane potential and dipeptidylpeptidase-4 activity in living animals

Microfluidic high-content phenotypic screening on a Caenorhabditis elegans model

Analysis of cellular and drug action mechanisms in the malaria parasites using systems biology approaches

Reprogramming the B1 Domain of Streptococcal Protein G (GB1)

Semisynthetic Biosensors for the Quantification of Nicotinamide Adenine Dinucleotides in Live Cells

The evolution of multiple active site configurations in a designed enzyme

Toward a unified scoring function for native state discrimination and drug-binding pocket recognition

Single-Cell Droplet Microfluidic Screening for Antibodies Specifically Binding to Target Cells

SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein-Coupled Receptor via a Remotely Tethered Photoswitchable Ligand

Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis