Concept

Drug design

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Drug design

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Artificial intelligence for natural product drug discovery

Asymmetric Construction of alpha,alpha-Disubstituted Piperazinones Enabled by Benzilic Amide Rearrangement

Asymmetric Construction of α,α‐Disubstituted Piperazinones Enabled by Benzilic Amide Rearrangement

A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers

Nanomole-scale photochemical thiol-ene chemistry for high-throughput late-stage diversification of peptide macrocycles

Optimised three-dimensional in vitro retinoblastoma models tailored for drug discovery and clinical translatability

De novo protein design by inversion of the AlphaFold structure prediction network

Method for hormone or drug screening in a tissue sample

The predictive capacity of in vitro preclinical models to evaluate drugs for the treatment of retinoblastoma

Motifs for making tricycles