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Spliceosomal small nuclear ribonucleoproteins (snRNPs), comprised of small nuclear RNAs (snRNAs) in complex with snRNP-specific proteins, are essential for pre-mRNA splicing. Coilin is not a snRNP protein but concentrates snRNPs and their assembly intermed ...
Background: Coupled biological oscillators can tick with the same period. How this collective period is established is a key question in understanding biological clocks. We explore this question in the segmentation clock, a population of coupled cellular o ...
Hox genes encode transcription factors essential for patterning the anterior to posterior animal body axis. In vertebrates, these genes are arranged in clusters. During development, Hox genes are activated in a time sequence that follows their physical ord ...
A species-specific number of segments is a hallmark of the vertebrate body plan. The first segmental structures in the vertebrate embryo are the somites, which bud sequentially from the growing presomitic mesoderm (PSM). The Clock and Wavefront model for s ...
Rhythmic and sequential subdivision of the elongating vertebrate embryonic body axis into morphological somites is controlled by an oscillating multicellular genetic network termed the segmentation clock. This clock operates in the presomitic mesoderm (PSM ...
Hox genes are central to the specification of structures along the anterior-posterior body axis, and modifications in their expression have paralleled the emergence of diversity in vertebrate body plans. Here we describe the genomic organization of Hox clu ...
The segmentation of Drosophila is a prime model to study spatial patterning during embryogenesis. The spatial expression of segment polarity genes results from a complex network of interacting proteins whose expression products are maintained after success ...
Biomechanics analysis of the ski jump is highly required. Some parameters and their interrelations have been reported in previous research studies limited to few athletes. The generalization of these parameters to athletes of various levels and under train ...
3D kinematic and dynamic analysis is highly required in ski jumping. Current recording techniques (e.g. camera systems) suffered from limitations, such as volume capture or complexity of use and processing. This study proposed a new 3D approach based on in ...
A central tenet of embodied artificial intelligence is that intelligent behavior arises out of the coupled dynamics between an agent's body, brain and environment. It follows that the complexity of an agents's controller and morphology must match the compl ...
