Related publications (10)

Roles of Clinical Features and Chest CT in Predicting the Outcomes of Hospitalized Patients with COVID-19 Developing AKI

Ali Falsafi, Shekoofeh Yaghmaei

This research aimed to evaluate the clinical features and computed tomography (CT) scans associated with poor outcomes in COVID-19 patients with acute kidney injury (AKI). A total of 351 COVID-19 patients (100 AKI, 251 non-AKI) hospitalized at Imam Hossein ...
IRANIAN SOC NEPHROLGY2023

Polymeric Micelles Loading Proteins through Concurrent Ion Complexation and pH-Cleavable Covalent Bonding for In Vivo Delivery

Francesco Stellacci, Suiyang Liao

Protein drugs have great potential as targeted therapies, yet their application suffers from several drawbacks, such as instability, short half-life, and adverse immune responses. Thus, protein delivery approaches based on stimuli-responsive nanocarriers c ...
WILEY-V C H VERLAG GMBH2019

A Murine Model of Robotic Training to Evaluate Skeletal Muscle Recovery after Injury

Silvestro Micera, Stefano Lai

LAI, S., A. PANARESE, R. LAWRENCE, M. L. BONINGER, S. MICERA, and F. AMBROSIO. A Murine Model of Robotic Training to Evaluate Skeletal Muscle Recovery after Injury. Med. Sci. Sports Exerc., Vol. 49, No. 4, pp. 840-847, 2017. Purpose: In vivo studies have s ...
American College of Sports Medicine2017

Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4

Nikolaos Stergiopoulos

Auto-antibodies to apolipoprotein A-1 (anti-apoA-1 IgG) were shown to promote inflammation and atherogenesis, possibly through innate immune receptors signalling. Here, we aimed at investigating the role of Toll-like receptors (TLR) 2 and 4 on anti-apoA-1 ...
Schattauer Gmbh-Verlag Medizin Naturwissenschaften2015

Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1

Johan Auwerx

Aims Statins protect against cardiovascular-related mortality but induce skeletal muscle toxicity. To investigate mechanisms of statins, we tested the hypothesis that statins optimized cardiac mitochondrial function but impaired vulnerable skeletal muscle ...
Oxford University Press2012

Force transmission in migrating cells

Jean-Jacques Meister, Roger Sauser, Maxime Fred Maurice Fournier

During cell migration, forces generated by the actin cytoskeleton are transmitted through adhesion complexes to the substrate. To investigate the mechanism of force generation and transmission, we analyzed the relationship between actin network velocity an ...
2010

Characterization of pip5k3 fleck corneal dystrophy-linked gene in zebrafish

PIKfyve is a kinase encoded by pip5k3 involved in phosphatidylinositols (PdtIns) pathways. These lipids building cell membranes have structural functions and are involved in complex intracellular regulations. Mutations in human PIP5K3 are associated with F ...
2008

Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages

Nicola Harris, Benjamin John Marsland

Chronic obstructive pulmonary disease (COPD) is the 5(th) most prevalent disease worldwide leading to severe morbidity and mortality in developed countries. The disease is strongly associated with smoking, and can be characterized by progressive and irreve ...
2008

Structure and dynamics of actin network at the leading edge of migrating cells

Sébastien Schaub

Crawling motion is characteristic of most animal cells and is principally based on actin-myosin II cytoskeletal system. The major components and reactions contributing to motility have been identified, but the overall picture of how these molecular events ...
EPFL2006

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