Concept
European Americans
Related publications (10)
Calorie restriction slows age-related microbiota changes in an Alzheimer's disease model in female mice
Alzheimer's disease (AD) affects an estimated 5.8 million Americans, and advanced age is the greatest risk factor. AD patients have altered intestinal microbiota. Accordingly, depleting intestinal microbiota in AD animal models reduces amyloid-beta (A beta ...
Springer2019Role of APOBEC3F Gene Variation in HIV-1 Disease Progression and Pneumocystis Pneumonia
Jacques Fellay, Christian Axel Wandall Thorball, Istvan Bartha
Human APOBEC3 cytidine deaminases are intrinsic resistance factors to HIV-1. However, HIV-1 encodes a viral infectivity factor (Vif) that degrades APOBEC3 proteins. In vitro APO-BEC3F (A3F) anti-HIV-1 activity is weaker than A3G but is partially resistant ...
Public Library of Science2016Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil
Summary Understanding the peopling of the Americas remains an important and challenging question. Here, we present 14C dates, and morphological, isotopic and genomic sequence data from two human skulls from the state of Minas Gerais, Brazil, part of one of ...
Cell Press2014Why to account for finite sites in population genetic studies and how to do this with Jaatha 2.0
With the advent of next-generation sequencing technologies, large data sets of several thousand loci from multiple conspecific individuals are available. Such data sets should make it possible to obtain accurate estimates of population genetic parameters, ...
Wiley-Blackwell2013