Publications related to Dynein

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

Pierre Gönczy, Nicola Jane Dynes, Ashwani Sharma

Centrioles are fundamental and evolutionarily conserved microtubule-based organelles whose assembly is characterized by microtubule growth rates that are orders of magnitude slower than those of cytoplasmic microtubules. Several centriolar proteins can int ...

2016

Dynein Transmits Polarized Actomyosin Cortical Flows to Promote Centrosome Separation

Pierre Gönczy, Alessandro De Simone

The two centrosomes present at the onset of mitosis must separate in a timely and accurate fashion to ensure proper bipolar spindle assembly. The minus-end-directed motor dynein plays a pivotal role in centrosome separation, but the underlying mechanisms r ...

Elsevier2016

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Pierre Gönczy, Georgios Hatzopoulos, Paul Guichard

Centrioles are microtubule-based structures that play important roles notably in cell division and cilium biogenesis. CEP135/Bld10p family members are evolutionarily conserved microtubule-binding proteins important for centriole formation. Here, we analyze ...

Elsevier2016

Aurora A kinase regulates proper spindle positioning in C-elegans and in human cells

Pierre Gönczy, Coralie Busso, Sachin Kotak

Accurate spindle positioning is essential for error-free cell division. The one-cell Caenorhabditis elegans embryo has proven instrumental for dissecting mechanisms governing spindle positioning. Despite important progress, how the cortical forces that act ...

2016

Fundamental Constraints on the Abundances of Chemotaxis Proteins

Anne-Florence Raphaëlle Bitbol

Flagellated bacteria, such as Escherichia coli, perform directed motion in gradients of concentration of attractants and repellents in a process called chemotaxis. The E. coli chemotaxis signaling pathway is a model for signal transduction, but it has uniq ...

Elsevier BV2015

Flagellar membranes are rich in raft-forming phospholipids

Adrian Schmid

The observation that the membranes of flagella are enriched in sterols and sphingolipids has led to the hypothesis that flagella might be enriched in raft-forming lipids. However, a detailed lipidomic analysis of flagellar membranes is not available. Novel ...

Company Of Biologists Ltd2015

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane

Pierre Gönczy, Coralie Busso, Sachin Kotak

The positioning and the elongation of the mitotic spindle must be carefully regulated. In human cells, the evolutionary conserved proteins LGN/Gai1-3 anchor the coiled-coil protein NuMA and dynein to the cell cortex during metaphase, thus ensuring proper s ...

2014

Clathrin regulates centrosome positioning by promoting acto-myosin cortical tension in C. elegans embryos

Pierre Gönczy, Alessandro De Simone, Sylvain Träger, Kalyani Thyagarajan

Regulation of centrosome and spindle positioning is crucial for spatial cell division control. The one-cell Caenorhabditis elegans embryo has proven attractive for dissecting the mechanisms underlying centrosome and spindle positioning in a metazoan organi ...

Company Of Biologists Ltd2014

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Dynein

Mechanisms of centrosome separation in C. elegans

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

Dynein Transmits Polarized Actomyosin Cortical Flows to Promote Centrosome Separation

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Aurora A kinase regulates proper spindle positioning in C-elegans and in human cells

Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg Extracts

Fundamental Constraints on the Abundances of Chemotaxis Proteins

Flagellar membranes are rich in raft-forming phospholipids

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane

Clathrin regulates centrosome positioning by promoting acto-myosin cortical tension in C. elegans embryos

Graph Chatbot

Chat with Graph Search

Dynein Transmits Polarized Actomyosin Cortical Flows to Promote Centrosome Separation

Fundamental Constraints on the Abundances of Chemotaxis Proteins

Mechanisms of centrosome separation in C. elegans

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Aurora A kinase regulates proper spindle positioning in C-elegans and in human cells

Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg Extracts

Flagellar membranes are rich in raft-forming phospholipids

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane

Clathrin regulates centrosome positioning by promoting acto-myosin cortical tension in C. elegans embryos