Publications related to Antiarrhythmic agent

Severe and uniform bi-atrial remodeling measured by dominant frequency analysis in persistent atrial fibrillation unresponsive to ablation

Jean-Marc Vesin, Adrian Luca, Andréa Buttu, Etienne Pruvot

Background High values of ECG and intracardiac dominant frequency (DF) are indicative of significant atrial remodeling in persistent atrial fibrillation (peAF). We hypothesized that patients with peAF unresponsive to ablation display higher ECG and intraca ...

2019

From Patients to Platelets and Back Again: Pharmacological Approaches to Glycoprotein VI, a Thrilling Antithrombotic Target with Minor Bleeding Risks

Nikolaos Stergiopoulos, Augusto Martins Lima

Despite significant advances in the treatment of thrombogenic diseases, antiplatelet therapies are still associated with a high bleeding risk. Consequently, potential benefits of preventing thromboembolic events by pharmacological agents need to be balance ...

GEORG THIEME VERLAG KG2019

An Adaptive Organization Index to Characterize Atrial Fibrillation using Wrist-Type Photoplethysmographic Signals

Jean-Marc Vesin, Mathieu Lemay, Célestin Leupi, Sibylle Fallet, Etienne Pruvot, Philippe Renevey

The performance of photoplethysmography (PPG)- based wearable monitors to diagnose atrial fibrillation (AF) remains unknown to date. This study aims at assessing the performance of new indices quantifying the level of organization in PPG signals to diagnos ...

2016

Impact of Conduction Velocity on Local Capture of Atrial Fibrillation Induced by Rapid Pacing

Jean-Marc Vesin, Adrian Luca, Alexandru Rusu

Objectives: Rapid pacing of atrial fibrillation (AF) can induce local atrial capture. The present model-based study investigated the impact of atrial tissue conduction velocity on AF capture ability during rapid septal pacing. Methods: The AF model combine ...

2015

Intermittent Atrial Tachycardia Promotes Repolarization Alternans and Conduction Slowing During Rapid Rates, and Increases Susceptibility to Atrial Fibrillation in a Free-Behaving Sheep Model

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Repolarization Alternans and Atrial Remodeling Introduction Paroxysmal atrial fibrillation (AF) may be triggered by intermittent atrial tachycardia, and ultimately lead to persistent AF. However, the mechanisms by which intermittent atrial tachycardia prom ...

Wiley-Blackwell2014

Kinetics of Atrial Repolarization Alternans in a Free-Behaving Ovine Model

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Kinetics of Atrial Repolarization Alternans. Introduction: Repolarization alternans (Re-ALT), a beat-to-beat alternation in action potential repolarization, promotes dispersion of repolarization, wavebreaks, and reentry. Recently, Re-ALT has been shown to ...

Wiley-Blackwell2012

Harmonic frequency tracking algorithm for predicting the success of pharmacological cardioversion of atrial fibrillation

Jean-Marc Vesin, Laurent Renaud Uldry, Andréa Buttu, Jérôme Sébastien Van Zaen, Lukas Kappenberger

Purpose: Non-invasively predicting the success of pharmacological cardioversion for patients with atrial fibrillation (AF) would be of great interest in clinical settings. In this study, an adaptive algorithm for tracking fundamental and harmonic component ...

2011

Decreased Excitability as a Protective Mechanism Against Repolarization Alternans-Induced Atrial Reentry

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Introduction: We recently observed in human left atrium periods of intermittent 2:1 and 1:1 atrial capture, preceded by atrial repolarization alternans (Re-ALT) during rapid pacing. It remains undetermined whether Re- ALT plays a role in preventing 1:1 atr ...

2010

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Antiarrhythmic agent

Severe and uniform bi-atrial remodeling measured by dominant frequency analysis in persistent atrial fibrillation unresponsive to ablation

From Patients to Platelets and Back Again: Pharmacological Approaches to Glycoprotein VI, a Thrilling Antithrombotic Target with Minor Bleeding Risks

An Adaptive Organization Index to Characterize Atrial Fibrillation using Wrist-Type Photoplethysmographic Signals

Impact of Conduction Velocity on Local Capture of Atrial Fibrillation Induced by Rapid Pacing

Intermittent Atrial Tachycardia Promotes Repolarization Alternans and Conduction Slowing During Rapid Rates, and Increases Susceptibility to Atrial Fibrillation in a Free-Behaving Sheep Model

Correlation Dimension as a Measure of the Atrial Fibrillation Capture during Atrial Septal Pacing

Kinetics of Atrial Repolarization Alternans in a Free-Behaving Ovine Model

Characterization of Atrial Repolarization Alternans and Activation Time Kinetics based on Intracardiac Electrograms

Harmonic frequency tracking algorithm for predicting the success of pharmacological cardioversion of atrial fibrillation

Decreased Excitability as a Protective Mechanism Against Repolarization Alternans-Induced Atrial Reentry

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Kinetics of Atrial Repolarization Alternans in a Free-Behaving Ovine Model

Severe and uniform bi-atrial remodeling measured by dominant frequency analysis in persistent atrial fibrillation unresponsive to ablation

From Patients to Platelets and Back Again: Pharmacological Approaches to Glycoprotein VI, a Thrilling Antithrombotic Target with Minor Bleeding Risks

Intermittent Atrial Tachycardia Promotes Repolarization Alternans and Conduction Slowing During Rapid Rates, and Increases Susceptibility to Atrial Fibrillation in a Free-Behaving Sheep Model

Correlation Dimension as a Measure of the Atrial Fibrillation Capture during Atrial Septal Pacing

Impact of Conduction Velocity on Local Capture of Atrial Fibrillation Induced by Rapid Pacing

Characterization of Atrial Repolarization Alternans and Activation Time Kinetics based on Intracardiac Electrograms

Harmonic frequency tracking algorithm for predicting the success of pharmacological cardioversion of atrial fibrillation

Decreased Excitability as a Protective Mechanism Against Repolarization Alternans-Induced Atrial Reentry

An Adaptive Organization Index to Characterize Atrial Fibrillation using Wrist-Type Photoplethysmographic Signals