Publications related to Cyclin-dependent kinase

Impact of Anion Asymmetry on Local Structure and Supercooling Behavior of Water-in-Salt Electrolytes

Salts with asymmetric (fluorosulfonyl)(trifluoromethanesulfonyl)imide (FTFSI) anions have recently been shown to suppress crystallization of water-in-salt electrolytes, enabling low-temperature operation of high-voltage aqueous rechargeable batteries. To c ...

AMER CHEMICAL SOC2020

Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13

Hilal Lashuel, Lara Petricca, Sean Michael Deguire

Huntington's disease (HD) is a progressive neurodegenerative disorder caused by an expansion of a CAG triplet repeat (encoding for a polyglutamine tract) within the first exon of the huntingtin gene. Expression of the mutant huntingtin (mHTT) protein can r ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2020

Identification of novel PCTAIRE-1/CDK16 substrates using a chemical genetic screen

Kei Sakamoto, Maria Deak, Caterina Collodet

PCTAIRE-1 (also known as cyclin-dependent protein kinase (CDK) 16), is a Ser/Thr kinase that has been implicated in many cellular processes, including cell cycle, spermatogenesis, neurite outgrowth, and vesicle trafficking. Most recently, it has been propo ...

2019

Dynamics of protein synthesis and degradation through the cell cycle

David Michael Suter, Andrea Brigitta Alber

Protein expression levels depend on the balance between their synthesis and degradation rates. Even quiescent (G(0)) cells display a continuous turnover of proteins, despite protein levels remaining largely constant over time. In cycling cells, global prot ...

TAYLOR & FRANCIS INC2019

Mapping the site-specific accuracy of loop-based local pulse wave velocity estimation and reflection magnitude: a 1D arterial network model analysis

Nikolaos Stergiopoulos, Patrick Segers

Objective: Local pulse wave velocity (PWV) can be estimated from the waterhammer equation and is an essential component of wave separation analysis. However, previous studies have demonstrated inaccuracies in the estimations of local PWV due to the presenc ...

2019

Flagellar microtubule doublet assembly in vitro reveals a regulatory role of tubulin C-terminal tails

Davide Demurtas, Paul Guichard, Virginie Hamel

Microtubule doublets (MTDs), consisting of an incomplete B-microtubule at the surface of a complete A-microtubule, provide a structural scaffold mediating intraflagellar transport and ciliary beating. Despite the fundamental role of MTDs, the molecular mec ...

AMER ASSOC ADVANCEMENT SCIENCE2019

An essential thioredoxin is involved in the control of the cell cycle in the bacterium Caulobacter crescentus

Camille Véronique Bernadette Goemans

Thioredoxins (Trxs) are antioxidant proteins that are conserved among all species. These proteins have been extensively studied and perform reducing reactions on a broad range of substrates. Here, we identified Caulobacter crescentus Trx1 (CCNA_03653; CcTr ...

2018

HIV-1 Vpr and p21 restrict LINE-1 mobility

Didier Trono, Priscilla Turelli, Flavia Marzetta

Long interspersed element-1 (LINE-1, L1) composes ∼17% of the human genome. However, genetic interactions between L1 and human immunodeficiency virus type 1 (HIV-1) remain poorly understood. In this study, we found that HIV-1 suppresses L1 retrotranspositi ...

2018

Physiological regulation of the CDK16/PCTAIRE-1 protein kinase and its proposed role in the brain

Saifeldin Nasser Mohamed Ibrahim Shehata

Cell signalling, mediated to a large extent by protein kinase phosphorylation, plays a vital role in regulation of cellular function. PCTAIRE-1 (also known as cyclin-dependent protein kinase (CDK)16), is a Ser/Thr kinase that has been implicated in many ce ...

EPFL2017

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Cyclin-dependent kinase

Impact of Anion Asymmetry on Local Structure and Supercooling Behavior of Water-in-Salt Electrolytes

Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13

Identification of novel PCTAIRE-1/CDK16 substrates using a chemical genetic screen

Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

Dynamics of protein synthesis and degradation through the cell cycle

Mapping the site-specific accuracy of loop-based local pulse wave velocity estimation and reflection magnitude: a 1D arterial network model analysis

Flagellar microtubule doublet assembly in vitro reveals a regulatory role of tubulin C-terminal tails

An essential thioredoxin is involved in the control of the cell cycle in the bacterium Caulobacter crescentus

HIV-1 Vpr and p21 restrict LINE-1 mobility

Physiological regulation of the CDK16/PCTAIRE-1 protein kinase and its proposed role in the brain

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Chat with Graph Search

Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

Impact of Anion Asymmetry on Local Structure and Supercooling Behavior of Water-in-Salt Electrolytes

Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13

Identification of novel PCTAIRE-1/CDK16 substrates using a chemical genetic screen

Dynamics of protein synthesis and degradation through the cell cycle

Mapping the site-specific accuracy of loop-based local pulse wave velocity estimation and reflection magnitude: a 1D arterial network model analysis

Flagellar microtubule doublet assembly in vitro reveals a regulatory role of tubulin C-terminal tails

HIV-1 Vpr and p21 restrict LINE-1 mobility

Physiological regulation of the CDK16/PCTAIRE-1 protein kinase and its proposed role in the brain

An essential thioredoxin is involved in the control of the cell cycle in the bacterium Caulobacter crescentus