Concept

Domain (biology)

Related publications (41)

Pde-Constrained Optimization For Nuclear Mechanics

We propose an image based PDE-constrained optimisation framework to compute the dynamical quantities of a cell nucleus undergoing deformation. It allows retrieving the displacement, strain and stress at each pixel of the nuclear domain, as well as the trac ...

IEEE2022

A non-twisting flux tube for local gyrokinetic simulations

Stephan Brunner, Justin Richard Ball

Local gyrokinetic simulations use a field-aligned domain that twists due to the magnetic shear of the background magnetic equilibrium. However, if the magnetic shear is strong and/or the domain is long, the twist can become so extreme that it fails to prop ...

2021

The Mammalian Membrane Microenvironment Regulates the Sequential Attachment of Bacteria to Host Cells

Alexandre Louis André Persat, Xavier Jean-Yves Pierrat

Pathogen attachment to host tissue is critical in the progress of many infections. Bacteria use adhesion in vivo to stabilize colonization and subsequently regulate the deployment of contact-dependent virulence traits. To specifically target host cells, th ...

2021

A New Chemoenzymatic Semisynthetic Approach Provides Insight into the Role of Phosphorylation beyond Exon1 of Huntingtin and Reveals N-Terminal Fragment Length-Dependent Distinct Mechanisms of Aggregation

Hilal Lashuel, Jonathan Jean-Pierre Ricci, Andreas Reif, Iman Rostami, Rajasekhar Kolla, Gopinath Pushparathinam

Huntington’s disease is a neurodegenerative dis- order caused by the expansion of a polyglutamine repeat (>36Q) in the N-terminal domain of the huntingtin protein (Htt), which renders the protein or fragments thereof more prone to aggregate and form inclus ...

2021

MATHICSE technical Report : A parabolic local problem with exponential decay of the resonance error for numerical homogenization

Doghonay Arjmand, Edoardo Paganoni

This paper aims at an accurate and ecient computation of eective quantities, e.g., the homogenized coecients for approximating the solu- tions to partial dierential equations with oscillatory coecients. Typical multiscale methods are based on a micro-macro ...

MATHICSE2020

On The Behavior Of Clamped Plates Under Large Compression

We determine the asymptotic behavior of eigenvalues of clamped plates under large compression by relating this problem to eigenvalues of the Laplacian with Robin boundary conditions. Using the method of fundamental solutions, we then carry out a numerical ...

2019

Chemometric Analysis of Bacterial Peptidoglycan Reveals Atypical Modifications That Empower the Cell Wall against Predatory Enzymes and Fly Innate Immunity

Bruno Lemaitre

Peptidoglycan is a fundamental structure for most bacteria. It contributes to the cell morphology and provides cell wall integrity against environmental insults. While several studies have reported a significant degree of variability in the chemical compos ...

American Chemical Society2016

Post-deposition control of ferroelastic stripe domains and internal electric field by thermal treatment

Nava Setter, Silviu Cosmin Sandu, Ludwig Feigl, Monika Iwanowska

The dependence of the formation of ferroelastic stripe domain patterns on the thermal history is investigated by detailed piezoresponse force microscopy and X-ray diffraction experiments after and during annealing of tensile strained tetragonal Pb(Ti,Zr)O- ...

American Institute of Physics2015

Single-Molecule Imaging Deciphers the Relation between Mobility and Signaling of a Prototypical G Protein-Coupled Receptor in Living Cells

Horst Vogel, Joachim Piguet, Luc Veya

Lateral diffusion enables efficient interactions between membrane proteins leading to signal transmission across the plasma membrane. An open question is how the spatio-temporal distribution of cell surface receptors influences the transmembrane signaling ...

American Society for Biochemistry and Molecular Biology2015

Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg Extracts

Christoph Merten

Nuclear size changes dynamically during development and has long been observed to correlate with the space surrounding the nucleus, as well as with the volume of the cell. Here we combine an in vitro cell-free system of Xenopus laevis egg extract with micr ...

2015

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