Chlorella is a genus of about thirteen species of single-celled green algae of the division Chlorophyta. The cells are spherical in shape, about 2 to 10 μm in diameter, and are without flagella. Their chloroplasts contain the green photosynthetic pigments chlorophyll-a and -b. In ideal conditions cells of Chlorella multiply rapidly, requiring only carbon dioxide, water, sunlight, and a small amount of minerals to reproduce. The name Chlorella is taken from the Greek χλώρος, chlōros/ khlōros, meaning green, and the Latin diminutive suffix ella, meaning small. German biochemist and cell physiologist Otto Heinrich Warburg, awarded with the Nobel Prize in Physiology or Medicine in 1931 for his research on cell respiration, also studied photosynthesis in Chlorella. In 1961, Melvin Calvin of the University of California received the Nobel Prize in Chemistry for his research on the pathways of carbon dioxide assimilation in plants using Chlorella. Chlorella has been considered as a source of food and energy because its photosynthetic efficiency can reach 8%, which exceeds that of other highly efficient crops such as sugar cane. Chlorella was first described by Martinus Beijerinck in 1890. Since then, over a hundred taxa have been described within the genus. However, biochemical and genomic data has revealed that many of these species were not closely related to each other, even being placed in a separate class Chlorophyceae. In other words, the "green ball" form of Chlorella appears to be a product of convergent evolution and not a natural taxon. Identifying Chlorella-like algae based on morphological features alone is generally not possible. Some strains of "Chlorella" used for food are incorrectly identified, or correspond to genera that were classified out of true Chlorella. For example, Heterochlorella luteoviridis is typically known as Chlorella luteoviridis which is no longer considered a valid name. Chlorella is a food source because it is high in protein and other essential nutrients; when dried, it is about 45% protein, 20% fat, 20% carbohydrate, 5% fiber, and 10% minerals and vitamins.

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