Concept

Membrane transport

Related publications (147)

Nonlinear microscopy for temporally and spatially resolved label-free imaging of living cells

The human brain consists of approximately a hundred billion of neurons that communicate through a unique series of biochemical and electrical processes. When neuronal networks are solicited, electrochemical processes happen involving millions of cells with ...

EPFL2018

RdhC, a family of membrane-bound flavoproteins involved in electron transfer in organohalide respiration ?

Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Géraldine Florence Buttet

Organohalide respiration (OHR) is a bacterial energy metabolism making use of halogenated compounds – like tetrachloroethene (PCE), a major pollutant – as terminal electron acceptors. Three models of electron transport chain exist for OHR [1], however many ...

2018

Assessing The Bioaccumulation Potential Of Ionizable Organic Compounds: Current Knowledge And Research Priorities

Kristin Schirmer

The objective of the present study was to review the current knowledge regarding the bioaccumulation potential of ionizable organic compounds (IOCs), with a focus on the availability of empirical data for fish. Aspects of the bioaccumulation potential of I ...

Society of Environmental Toxicology and Chemistry Press2017

Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor

Horst Vogel, Henning Paul-Julius Stahlberg, Rudolf Hovius, Cédric Deluz, Luigino Grasso, Romain Wyss, Ghérici Hassaïne, Sonja Minniberger

There is growing interest in the use of mammalian protein expression systems, and in the use of antibodyderived chaperones, for structural studies. Here, we describe protocols ranging from the production of recombinant membrane proteins in stable inducible ...

Springer New York2017

Abnormal creatine transport of mutations in monocarboxylate transporter 12 (MCT12) found in patients with age-related cataract can be partially rescued by exogenous chaperone CD147

Membrane transporters influence biological functions in the ocular lens. Here, we investigate the monocarboxylate transporter 12 (MCT12), also called creatine transporter 2 (CRT2), which is found in the ocular lens and is involved in cataract. As the age-r ...

Oxford Univ Press2017

Transcellular Pathways in Lymphatic Endothelial Cells Regulate Changes in Solute Transport by Fluid Stress

Marco Pisano, Valentina Triacca, Melody Swartz, Witold Waldemar Kilarski, Esra Güç

Rationale: The transport of interstitial fluid and solutes into lymphatic vessels is important for maintaining interstitial homeostasis and delivering antigens and soluble factors to the lymph node for immune surveillance. Transendothelial transport across ...

Lippincott Williams & Wilkins2017

Enhancing Structure Prediction and Design of Soluble and Membrane Proteins with Explicit Solvent-Protein Interactions

Patrick Daniel Barth

Solvent molecules interact intimately with proteins and can profoundly regulate their structure and function. However, accurately and efficiently modeling protein solvation effects at the molecular level has been challenging. Here, we present a method that ...

2017

Proteoliposomes - a system to study membrane proteins under buffer gradients by cryo-EM

Henning Paul-Julius Stahlberg

Membrane proteins are vital to life and major therapeutic targets. Yet, understanding how they function is limited by a lack of structural information. In biological cells, membrane proteins reside in lipidic membranes and typically experience different bu ...

Walter de Gruyter GmbH2017

Properties of Enzymes Involved in Tetrachloroethene Respiration

Géraldine Florence Buttet

Tetrachloroethene (PCE) pollution threatens nature and human health due to its toxic and carcinogenic potential. Due to industrial activities, large amounts of PCE were discharged into the environment over the last decades and represent one of major ground ...

EPFL2017

Sphingolipid metabolic flow controls phosphoinositide turnover at the trans ‐Golgi network

Giovanni D'Angelo, Howard Riezman, Riccardo Rizzo

Sphingolipids are membrane lipids globally required for eukaryotic life. The sphingolipid content varies among endomembranes with pre- and post-Golgi compartments being poor and rich in sphingolipids, respectively. Due to this different sphingolipid conten ...

2017

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