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Method Development towards Orthogonal Electrophile Delivery

Lingxi Wang

Redox signaling events mediated by reactive electrophilic species (RES) are key players in several cellular processes. However, the studies on RES have been challenging due to their high reactivity towards numerous nucleophilic groups present in the cells ...

EPFL2021

Declarative Variables in Online Dating: A Mixed-Method Analysis of a Mimetic-Distinctive Mechanism

Daniel Gatica-Perez, Jessica Carolina Pidoux

Declarative variables of self-description have a long-standing tradition in matchmaking media. With the advent of online dating platforms and their brand positioning, the volume and semantics of variables vary greatly across apps. However, a variable lands ...

2021

Molecular simulations of interfacial systems: challenges, applications and future perspectives

Athanasios Nenes, Satoshi Takahama, Mária Lbadaoui-Darvas

We present a comprehensive review of methods and applications of molecular simulations of interfacial systems. We give a detailed overview of the main techniques and major challenges in the following aspects of solid and fluid surfaces: adsorption at solid ...

TAYLOR & FRANCIS LTD2023

A semi-automated workflow paradigm for the distributed creation and curation of expert annotations

Martin Alois Rohrmeier, Fabian Claude Moss, Markus Franz Josef Neuwirth, Johannes Hentschel

The creation and curation of labeled datasets can be an arduous, expensive, and time-consuming task. We introduce a workflow paradigm for remote consensus-building between expert annotators, while considerably reducing the associated administrative overhea ...

2021

Implementation of Cognitive Digital Twins in Connected and Agile Supply Networks-An Operational Model

Dimitrios Kyritsis

Supply chain agility and resilience are key factors for the success of manufacturing companies in their attempt to respond to dynamic changes. The circular economy, the need for optimized material flows, ad-hoc responses and personalization are some of the ...

2021

Comparison Between Product and Process Oriented Zero-Defect Manufacturing (ZDM) Approaches

Dimitrios Kyritsis, Foivos Psarommatis Giannakopoulos

Contemporary manufacturing companies pay a lot of attention to product quality as this aspect affects directly their competitiveness, productivity and the reputation of the company. Traditional quality improvement methods such as Six Sigma, Lean etc. seems ...

SPRINGER INTERNATIONAL PUBLISHING AG2021

The Lean Startup Framework: Closing the Academic-Practitioner Divide

Marc Gruber

The lean startup framework is one of the most popular contributions in the practitioner-oriented entrepreneurship literature. This study seeks to generate new insights into how new ventures are started by describing the five main building blocks of the lea ...

SAGE PUBLICATIONS INC2020

ASAP 2020 update: an open, scalable and interactive web-based portal for (single-cell) omics analyses

Bart Deplancke, Vincent Roland Julien Gardeux, Fabrice David, Maria Litovchenko

Single-cell omics enables researchers to dissect biological systems at a resolution that was unthinkable just 10 years ago. However, this analytical revolution also triggered new demands in 'big data' management, forcing researchers to stay up to speed wit ...

2020

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