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Related publications (19)

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Epidemicity of cholera spread and the fate of infection control measures

Andrea Rinaldo, Cristiano Trevisin, Lorenzo Mari, Damiano Pasetto, Joseph Chadi Benoit Lemaitre, Marino Gatto

The fate of ongoing infectious disease outbreaks is predicted through reproduction numbers, defining the long-term establishment of the infection, and epidemicity indices, tackling the reactivity of the infectious pool to new contagions. Prognostic metrics ...

2022

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease

Mojgan Masoodi, Christopher Clark

Background Multiple pathophysiological processes have been described in Alzheimer's disease (AD). Their inter-individual variations, complex interrelations, and relevance for clinical manifestation and disease progression remain poorly understood. We hypot ...

BMC2021

Design and Development of Injectable, Tough and Intrinsically-Adhesive Hydrogels for Biomedical Applications

Peyman Karami

Despite the development of hydrogels with a wide range of mechanical properties, insufficient adhesion between these materials and biological surfaces limits their use in the biomedical applications. Most recent advancements in highly adhesive hydrogel sys ...

EPFL2021

DNA-based nanostructures are actively gaining interest as tools for biomedical and therapeutic applications following the recent development of protective coating strategies prolonging structural integrity in physiological conditions. For tailored biologic ...

AMER CHEMICAL SOC2021

Uncertainty reduction in biochemical kinetic models: Enforcing desired model properties

Vassily Hatzimanikatis, Ljubisa Miskovic, Michaël Roger Germain Moret

A persistent obstacle for constructing kinetic models of metabolism is uncertainty in the kinetic properties of enzymes. Currently, available methods for building kinetic models can cope indirectly with uncertainties by integrating data from different biol ...

2019

A Microfluidic Biodisplay

Sebastian Maerkl, Francesca Volpetti, Ekaterina Emilova Petrova

Synthetically engineered cells are powerful and potentially useful biosensors, but it remains problematic to deploy such systems due to practical difficulties and biosafety concerns. To overcome these hurdles, we developed a microfluidic device that serves ...

American Chemical Society2017

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Kinetic models are essential for studying complex behavior and properties of metabolism. However, a persistent hurdle for constructing these models is uncertainty in the kinetic properties of enzymes. Currently available methods for building kinetic models ...

2016

On the bioavailability of trace metals in surface sediments: a combined geochemical and biological approach

The bioavailability of metals was estimated in three river sediments (Sens,e, Scarpe, and DeA >> le Rivers) impacted by different levels of Cu, Cd, Pb, and Zn (Northern France). For that, a combination of geochemistry and biological responses (bacteria and ...

Springer Heidelberg2016

Infectious diseases pose a serious threat to public health due to its high infectivity and potentially high mortality. One of the most effective ways to protect people from being infected by these diseases is through vaccination. However, due to various re ...

Ieee-Inst Electrical Electronics Engineers Inc2016

Privacy is defined as the right to control, edit, manage, and delete information about oneself and decide when, how, and to what extent this information is communicated to others. Therefore, every person should ideally be empowered to manage and protect hi ...

EPFL2015