Publications related to Chemokine receptor

DL4-mediated Notch signaling is required for the development of fetal alpha beta and gamma delta T cells

Freddy Radtke, Ute Koch, Stéphanie Claudinot

T-cell development depends upon interactions between thymocytes and thymic epithelial cells (TECs). The engagement of delta-like 4 (DL4) on TECs by Notch1 expressed by blood-borne BM-derived precursors is essential for T-cell commitment in the adult thymus ...

Wiley-Blackwell2013

Role of Renin-Angiotensin System in Inflammation, Immunity and Aging

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Luciano Dos Santos Aggum Capettini

Recent data support the idea that the effects of RAS are not restricted to the cardiovascular and renal systems. Importantly, RAS modulates free radical production and the cellular synthesis of several molecules such as cytokines, chemokines and transcript ...

Bentham Science Publishers2012

KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function

Didier Trono, Isabelle Barde, Nicola Harris, Sandra Eloise Kjeldsen, Adamantia Kapopoulou, Andrea Corsinotti, Karolina Bojkowska

Chromatin remodeling is fundamental for B-cell differentiation. In the present study, we explored the role of KAP1, the cofactor of KRAB-ZFP transcriptional repressors, in this process. B-lymphoid-specific Kap1-KO mice displayed reduced numbers of mature B ...

2012

Update on the Role of Cannabinoid Receptors after Ischemic Stroke

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Luciano Dos Santos Aggum Capettini

Cannabinoids are considered as key mediators in the pathophysiology of inflammatory diseases, including atherosclerosis. In particular, they have been shown to reduce the ischemic injury after acute cardiovascular events, such as acute myocardial infarctio ...

Taylor & Francis2012

Exploiting Ligand-Protein Conjugates to Monitor Ligand-Receptor Interactions

Kai Johnsson, Hirohito Haruki, Monica Rengifo Gonzalez

We introduce three assays for analyzing ligand-receptor interactions based on the specific conjugation of ligands to SNAP-tag fusion proteins. Conjugation of ligands to different SNAP-tag fusions permits the validation of suspected interactions in cell ext ...

Public Library of Science2012

Evidence of dysregulation of dendritic cells in primary HIV infection

Jacques Fellay, Marie Larsson, Nan Hu

Myeloid and plasmacytoid dendritic cells (DCs) are important mediators of both innate and adaptive immunity against pathogens such as HIV. During the course of HIV infection, blood DC numbers fall substantially. In the present study, we sought to determine ...

2010

Epidermal {gamma}{delta} T cells sense precancerous cellular dysregulation and initiate immune responses

Freddy Radtke

Hyperplasia associated with a loss of tissue homeostasis can induce DNA replication stress, leading to precancerous dysregulation. Epidermal {gamma}{delta} T cells reside in the primary barrier that protects against diverse environmental insults; however, ...

Oxford University Press2010

Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype

Melody Swartz, Amine Issa

Most carcinomas spread to distant sites through lymphatic vessels. Several preclinical and clinical studies have shown a positive correlation between the incidence of lymph node metastasis and secretion of the lymphatic growth factor vascular endothelial g ...

American Association for Cancer Research2009

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Chemokine receptor

DL4-mediated Notch signaling is required for the development of fetal alpha beta and gamma delta T cells

Role of Renin-Angiotensin System in Inflammation, Immunity and Aging

KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function

Update on the Role of Cannabinoid Receptors after Ischemic Stroke

Exploiting Ligand-Protein Conjugates to Monitor Ligand-Receptor Interactions

Inflammasomes: current understanding and open questions

Evidence of dysregulation of dendritic cells in primary HIV infection

Biophysical Regulation of Lymphatic Vessel Function

Epidermal {gamma}{delta} T cells sense precancerous cellular dysregulation and initiate immune responses

Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype

Graph Chatbot

Chat with Graph Search

Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype

Exploiting Ligand-Protein Conjugates to Monitor Ligand-Receptor Interactions

Inflammasomes: current understanding and open questions

DL4-mediated Notch signaling is required for the development of fetal alpha beta and gamma delta T cells

Evidence of dysregulation of dendritic cells in primary HIV infection

Epidermal {gamma}{delta} T cells sense precancerous cellular dysregulation and initiate immune responses

Role of Renin-Angiotensin System in Inflammation, Immunity and Aging

KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function

Update on the Role of Cannabinoid Receptors after Ischemic Stroke

Biophysical Regulation of Lymphatic Vessel Function