Concept
Affymetrix
Related publications (17)
Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations
Jacques Fellay, Zhi Ming Xu, Sina Rüeger
Genome-wide association studies rely on the statistical inference of untyped variants, called imputation, to increase the coverage of genotyping arrays. However, the results are often suboptimal in populations underrepresented in existing reference panels ...
San Francisco2022Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each
Lukas Kühn, Giovanna Ambrosini, Barbara Grisoni-Neupert, Philipp Bucher, Ramona Pauchard-Batschulat, Otto Hagenbüchle
Regulation of mRNA stability by RNA-protein interactions contributes significantly to quantitative aspects of gene expression. We have identified potential mRNA targets of the AU-rich element binding protein AUF1. Myc-tagged AUF1 p42 was induced in mouse N ...
PUBLIC LIBRARY SCIENCE2018HDAC4 Does Not Act as a Protein Deacetylase in the Postnatal Murine Brain In Vivo
Reversible protein acetylation provides a central mechanism for controlling gene expression and cellular signaling events. It is governed by the antagonistic commitment of two enzymes families: the histone acetyltransferases (HATs) and the histone deacetyl ...
Public Library Science2013Personal receptor repertoires: olfaction as a model
Background: Information on nucleotide diversity along completely sequenced human genomes has increased tremendously over the last few years. This makes it possible to reassess the diversity status of distinct receptor proteins in different human individual ...
BioMed Central2012An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells
Cathrin Brisken, Stéphanie Joëlle André, Maryse Fiche
INTRODUCTION: About 70% of breast cancers express oestrogen receptor alpha (ESR1/ERalpha) and are oestrogen-dependent for growth. In contrast with the highly proliferative nature of ERalpha-positive tumour cells, ERalpha-positive cells in normal breast tis ...
2007