Concept

Injection (medicine)

Related publications (90)

Extraction of fluids to mitigate the seismic risk associated with post-injection aseismic slip

Subsurface fluid injections are commonly accompanied by seismicity which can sometimes result in earthquakes of relatively large magnitude that pose a serious hazard for the geo-energy industry. Current efforts to manage the seismic risk associated with fl ...

2023

Developing spinal circuits generate patterned motor outputs while many neurons with high membrane resistances are still maturing. In the spinal cord of hatchling frog tadpoles of unknown sex, we found that the firing reliability in swimming of inhibitory i ...

SOC NEUROSCIENCE2023

Novel trehalose-based excipients for stabilizing nebulized anti-SARS-CoV-2 antibody

Sandrine Gerber, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard

COVID-19 is caused by the infection of the lungs by SARS-CoV-2. Monoclonal antibodies, such as sotrovimab, showed great efficiency in neutralizing the virus before its internalization by lung epithelial cells. However, parenteral routes are still the prefe ...

2022

Laser-induced liquid micro-jets for drug delivery

Jan Krizek

Jet injection devices have been studied and developed for transdermal drug delivery to avoid the use of needles. Such contact-less devices provide several advantages such as better dose control, lateral and depth localisation, lower collateral damage than ...

EPFL2021

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Development of needle-free methods to administer injectable therapeutics has been researched for a few decades. We focused our attention on a laser-based jet injection technique where the liquid-jet actuation mechanism is based on optical cavitation. This ...

2021

A 510-pW 32-kHz Crystal Oscillator With High Energy-to-Noise-Ratio Pulse Injection

Kyojin Choo, Li Xu

This article introduces a 32-kHz crystal oscillator (XO) with high energy-to-noise-ratio pulse injection at subharmonic frequency. A T/4-delay clock slicer is proposed to convert the sinusoidal crystal waveform into an output clock of 32 kHz and to introdu ...

IEEE2021

Repetitive regime of highly focused liquid microjets for needle-free injection

Christophe Moser, Paul Delrot, Jan Krizek

Fast liquid jets are investigated for use as a needle-free drug delivery system into an elastic tissue such as skin. Using smaller jet diameters in a repetitive regime can mitigate bruising and pain associated with current injectors. In this study, we aim ...

2020

Needle-free delivery of fluids from compact laser-based jet injector

Christophe Moser, Paul Delrot, Jan Krizek

Jet injection devices have been studied and developed for transdermal drug delivery to avoid the use of needles. Due to bulky actuation mechanisms, they are limited to body areas that are easy to reach such as skin. Here, we demonstrate a thin and long liq ...

2020

Studying the interactions between electro-magnetic elds and biological tissue

Laurine Kolly

Drug delivery systems (DDS) were engineered to overcome the drawbacks of more common methods such as oral pills and intravenous injections. Implantable capsules that release anesthetic drugs locally for pain management after Total Knee Arthroplasty (TKA) a ...

2020

Bistable Puncturing Tool for Retinal Vein Cannulation

Yves Bellouard, Simon Nessim Henein, Charles Baur, Lisa Anaïs Jeanne Bonnefoy

An innovative surgical tool prototype dedicated to safe puncturing has been developed for the treatment of retinal vein occlusions (RVOs). The tool is manufactured monolithically by femtolaser printing in fused silica. It consists of a programmable bistabl ...

2020

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