Concept

Spinal disc herniation

Related publications (75)

Design methodology and numerical optimization of ultrasonic transducers for spinal surgery

Nowadays, the general trend towards to minimally invasive interventions is present in all the medical domains. For the surgical intervertebral spinal disc cutting or removal domain, it is particularly a necessity because the manual methods currently employ ...

EPFL2009

Does hydrogel-cell construct viscoelasticity affect ECM production?

Line Aschwanden

Low back pain is one of the most prevailing medical concerns and can often be associated with the degeneration of the intervertebral disc. This degeneration results in a loss of biological and mechanical properties, especially a loss of viscoelastic proper ...

2009

Does viscoelasticity of a Hydrogel-cell construct affect ECM production?

Dominique Pioletti, Arne Christian Vogel, Line Aschwanden

Intervertebral disc (IVD) degeneration is one of the prevailing medical concern and actual health cost. Industries and academic institutions research for therapeutic solutions going from drugs to complete and partial arthroplasty devices as well as enginee ...

2009

Soft-tissue viscoelasticity: extension to anisotropy and finite element implementation

Dominique Pioletti, Arne Christian Vogel

Physiological loading result to finite and finite rate of deformations of soft tissues such as ligament, tendons, and the annulus fibrosus of the intervertebral disc. Under these conditions, these soft tissues exhibit viscoelastic effects such as strain-st ...

2009

Virtual reality simulator for the training of lumbar punctures

Friedhelm Christoph Hummel

Lumbar puncture (LP) is performed by inserting a needle into the spinal canal to extract cerebrospinal fluid for diagnostic purposes. A virtual reality (VR) lumbar puncture simulator based on real patient data has been developed and evaluated. ...

Schattauer2009

Fetal cells for intervertebral disc regeneration

Aurélie Quintin

Degeneration of the intervertebral disc (IVD) is thought to be one main factor in the development of back pain. It is not a symptom by itself but can lead to painful pathological conditions. Current treatments aim at relieving pain by conservative care, me ...

EPFL2009

Isolation and in vitro chondrogenic potential of human fetal spine cells

Dominique Pioletti, Corinne Scaletta, Sandra Jaccoud, Aurélie Quintin

Cell therapy for nucleus pulposus regeneration is an attractive treatment for early disc degeneration as shown by studies using autologous nucleus pulposus cells or stem cells. Another potential source of cells is fetal cells. We investigated the feasibili ...

2009

Degeneration of the intervertebral discs : Effects of Mechanical Stress on Intervertebral Disc Cells ; Selection of a Cell Carrier for the In Vivo Delivery of Fetal Spine Cells

Valérie Loewensberg

[...] Low back pain affects nearly 80% the population at least once in their lifetime. Intervertebral disc (IVD) degeneration is thought to play a role in the development and onset of low back pain. The center part of the disc, the nucleus pulposus (NP), w ...

2008

Selection of a cell carrier for the in vivo delivery of fetal spine cells

Valérie Loewensberg

Objective: Several cell carriers need to be selected and characterized for their compatibility with fetal cartilaginous cell survival and activity. In order to assess the in vivo regeneration capacity of fetal cartilaginous cells, these cell carriers will ...

2008

Hydrogel viscoelasticity: identification of dissipation sources

Dominique Pioletti, Arne Christian Vogel, Philippe Gaillard

2008

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