Concept
Hierarchical Taxonomy of Psychopathology
Related publications (12)
Machine learning and its impact on psychiatric nosology: Findings from a qualitative study among German and Swiss experts
The increasing integration of Machine Learning (ML) techniques into clinical care, driven in particular by Deep Learning (DL) using Artificial Neural Nets (ANNs), promises to reshape medical practice on various levels and across multiple medical fields. Mu ...
2023Sex Differences in Comorbidity Combinations in the Swedish Population
High comorbidity rates, especially mental-physical comorbidity, constitute an increasing health care burden, with women and men being differentially affected. To gain an overview of comorbidity rates stratified by sex across a range of different conditions ...
MDPI2022Exploring associations between diurnal cortisol, stress, coping and psychopathology in adolescents and young adults with 22q11.2 deletion syndrome
Maria del Carmen Sandi Perez, Olivia Zanoletti, Maude Schneider, Farnaz Delavari
Background: 22q11.2 deletion syndrome (22q11DS) is a neurogenetic condition associated to a high risk for psychiatric disorders, including psychosis. Individuals with 22q11DS are thought to experience increased levels of chronic stress, which could lead to ...
2022Identifying Disease-Specific Neural Reactivity to Psychosocial Stress in Borderline Personality Disorder
Dimitri Nestor Alice Van De Ville
BACKGROUND: Patients with borderline personality disorder (BPD) typically present emotion dysregulation (ED) when faced with adversity. However, it is argued that altered stress response may be more influenced by ED than BPD-specific traits. Here, we inves ...
ELSEVIER2022Therapeutic potential of glutathione-enhancers in stress-related psychopathologies
Maria del Carmen Sandi Perez, Sarah Catherine Sonnay, Fiona Hollis, Pascal Steiner, Ioannis Zalachoras, Eva Ramos Fernandez, Laia Morato Fornaguera
The mammalian brain has high energy demands, which may become higher in response to environmental challenges such as psychogenic stress exposure. Therefore, efficient neutralization of reactive oxygen species that are produced as a by-product of ATP synthe ...
2020Developmental Trajectories of Cortical Thickness in Relation to Schizotypy During Adolescence
Investigating potential gray matter differences in adolescents presenting higher levels of schizotypy personality traits could bring further insights into the development of schizophrenia spectrum disorders. Research has yet to examine the morphological co ...
2020The diagnostic potential of multimodal neuroimaging measures in Parkinson's disease and atypical parkinsonism
Introduction For the diagnosis of Parkinson's disease (PD) and atypical parkinsonism (AP) using neuroimaging, structural measures have been largely employed since structural abnormalities are most noticeable in the diseases. Functional abnormalities have b ...
WILEY2020Stress Impacts the Regulation Neuropeptides in the Rat Hippocampus and Prefrontal Cortex
Gregor Rainer, Laura Lozano Montes, Nan Zhao
Adverse life experience increases the lifetime risk to several stress-related psychopathologies, such as anxiety or depressive–like symptom following stress in adulthood. However, the neurochemical modulations triggered by stress have not been fully charac ...
2018Wearable sensors objectively measure gait parameters in Parkinson's disease
Distinct gait characteristics like short steps and shuffling gait are prototypical signs commonly observed in Parkinson's disease. Routinely assessed by observation through clinicians, gait is rated as part of categorical clinical scores. There is an incre ...
2017A Functional Group Approach for Prediction of APPI Response of Organic Synthetic Targets
Yury Tsybin, Laure Menin, Konstantin Zhurov, Thomas Clément Di Franco
Atmospheric pressure photoionization (APPI) is a technique of choice for ionization of non-polar molecules in mass spectrometry (MS). Reported APPI-based studies tend to focus on a selected compound class, which may contain a variety of functional groups. ...
Springer2015