1–500 AD (approximately) – Nursing care palliative needs of persons and families. Religious organizations were the care providers. 55 AD – Phoebe was nursing history's Christian first nurse and most noted deaconess. 300 – Entry of Christian women into nursing. c. 390 AD – The first general hospital was established in Rome by Saint Fabiola. c. 620 AD – Rufaida Al-Aslamia became the first Muslim nurse. 1517 The Protestant Reformation – the breakdown of religious orders meant that monasteries, hospitals and nursing care facilities were closed in most Protestant areas. 1618–1648 – The Thirty Years' War – Catholic–Protestant wars rocked Europe, killing 8 million. 1633 – The founding of the Daughters of Charity of Saint Vincent de Paul, Servants of the Sick Poor by Sts. Vincent de Paul and Louise de Marillac. The community would not remain in a convent, but would nurse the poor in their homes, "having no monastery but the homes of the sick, their cell a hired room, their chapel the parish church, their enclosure the streets of the city or wards of the hospital." 1645 – French nurse Jeanne Mance established Hôtel-Dieu de Montréal, North America's first hospital. 1654 and 1656 – Sisters of Charity cared for the wounded on the battlefields at Sedan and Arras in France. 1660 – Over 40 houses of the Sisters of Charity existed in France and several in other countries; the sick poor were helped in their own houses in 26 parishes in Paris. The 18th century was considered the Age of Reason. A lot of myths were contradicted by scientific fact. Jamaican "doctresses" such as Cubah Cornwallis, Sarah Adams and Grace Donne, the mistress and healer to Jamaica's most successful planter, Simon Taylor, had great success using hygiene and herbs to heal the sick and wounded. 1805 – Mary Seacole is born in the Colony of Jamaica, as Mary Grant, the daughter of Mrs Grant, a successful Jamaican doctress with a reputation for healing the sick and wounded in that island, using hygiene and herbs. 1811 – The grand re-opening of Sydney Hospital (founded 1788 as a tent hospital).