Stefano SpaccapietraStefano Spaccapietra is a full professor at EPFL, Switzerland, where he has been heading the database laboratory. He has been in academic positions all along his career. He got his PhD from the University of Paris VI, in 1978, where he first had his master in Computer Science in 1969. At that time, he has been teaching file systems, later turned into teaching database systems. He moved to the University of Burgundy, Dijon, in 1983 to take a professor position at the Institute of Technology. He left Dijon for EPFL in 1988.
Prof. Spaccapietra is a Fellow of the IEEE and recipient of the IFIP Silver Core Award and ER Award. He is an ER fellow.
He has been Editor-in-chief of the Journal of Data Semantics (LNCS subline), Springer.
He is member of the editorial boards of the Data and Knowledge Engineering Journal (Elsevier), the
Internet and Web Information Systems Journal (Kluwer), the Revue Internationale de Géomatique (Hermes), and the Computing Letters Journal (CoLe), VSP/Brill.
He was former Chair of the IFIP Working Group 2.6 "Databases" and of the ER Conferences Steering Committee.
Auke IjspeertAuke Ijspeert is a full professor at the EPFL, and head of the Biorobotics Laboratory (BioRob). He has a B.Sc./M.Sc. in physics from the EPFL (1995), and a PhD in artificial intelligence from the University of Edinburgh (1999). He carried out postdocs at IDSIA and EPFL, and at the University of Southern California (USC). He then became a research assistant professor at USC, and an external collaborator at ATR (Advanced Telecommunications Research institute) in Japan. In 2002, he came back to the EPFL as an SNF assistant professor. He was promoted to associate professor in October 2009 and to full professor in April 2016. His primary affiliation is with the Institute of Bioengineering, and secondary affiliation with the Institute of Mechanical Engineering. His research interests are at the intersection between robotics, computational neuroscience, nonlinear dynamical systems, and machine learning. He is interested in using numerical simulations and robots to get a better understanding of sensorimotor coordination in animals, and in using inspiration from biology to design novel types of robots and adaptive controllers. (see for instance Ijspeert et al Science 2007, Ijspeert Science 2014, and Nyakatura et al Nature 2019). He is also investigating how to assist people with limited mobility using exoskeletons and assistive furniture. He is regularly invited to give talks on these topics (e.g. TED talk given at TED Global Geneva, Dec 8 2015). With his colleagues, he has received paper awards at ICRA2002, CLAWAR2005, IEEE Humanoids 2007, IEEE ROMAN 2014, CLAWAR 2015, SAB2018, and CLAWAR 2019. He is an IEEE Fellow, member of the Board of Reviewing Editors of Science magazine, and associate editor for the IEEE Transactions on Medical Robotics and Bionics and for the International Journal of Humanoid Robotics. He has acted as an associate editor for the IEEE Transactions on Robotics (2009-2013) and for Soft Robotics (2018-2021). He was a guest editor for the Proceedings of IEEE, IEEE Transactions on Biomedical Engineering, Autonomous Robots, IEEE Robotics and Automation Magazine, and Biological Cybernetics. He has been the organizer of 7 international conferences (BioADIT2004, SAB2004, AMAM2005, BioADIT2006, LATSIS2006, SSRR2016, AMAM2019), and a program committee member of over 50 conferences.
Marilyne AndersenMarilyne Andersen is a Full Professor of Sustainable Construction Technologies and heads the Laboratory of Integrated Performance in Design (LIPID) that she launched in the Fall of 2010. She was Dean of the School of Architecture, Civil and Environmental Engineering (ENAC) at EPFL from 2013 to 2018 and is the Academic Director of the Smart Living Lab in Fribourg. She also co-leads the Student Kreativity and Innovation Laboratory (SKIL) at ENAC. Before joining EPFL as a faculty, she was an Assistant Professor then Associate Professor tenure-track in the Building Technology Group of the MIT School of Architecture and Planning and the Head of the MIT Daylighting Lab that she founded in 2004. She has also been Invited Professor at the Singapore University of Technology and Design in 2019. Marilyne Andersen owns a Master of Science in Physics and specialized in daylighting through her PhD in Building Physics at EPFL in the Solar Energy and Building Physics Laboratory (LESO) and as a Visiting Scholar in the Building Technologies Department of the Lawrence Berkeley National Laboratory in California. Her research lies at the interface between science, engineering and architectural design with a dedicated emphasis on the impact of daylight on building occupants. Focused on questions of comfort, perception and health and their implications on energy considerations, these research efforts aim towards a deeper integration of the design process with daylighting performance and indoor comfort, by reaching out to various fields of science, from chronobiology and neuroscience to psychophysics and computer graphics. She is leveraging this research in practice through OCULIGHT dynamics, a startup company she co-founded, which offers specialized consulting services on daylight performance and its psycho-physiological effects on building occupants. She is the author of more than 200 papers published in peer-reviewed journals and international conferences and the recipient of several grants and awards including: the Daylight Award for Research (2016), eleven publication awards and distinctions (2009, 2011, 2012, 2015, 2018, 2019) including the Taylor Technical Talent Award 2009 granted by the Illuminating Engineering Society, the 3M Non-Tenured Faculty Grant (2009), the Mitsui Career Development Professorship at MIT (2008) and the EPFL prize of the Chorafas Foundation awarded to her PhD thesis in Sustainability (2005). Her research or teaching has been supported by professional, institutional and industrial organizations such as: the Swiss and the U.S. National Science Foundations, the Velux Foundation, the European Horizon 2020 program, the Boston Society of Architects, the MIT Energy Initiative and InnoSuisse. She was the leader and faculty advisor of the Swiss Team and its NeighborHub project, who won the U.S. Solar Decathlon 2017 competition with 8 podiums out of 10 contests. She is a member of the Board of the LafargeHolcim Foundation for Sustainable Construction and Head of its Academic Committee. She is also a member of the Editorial Board of the journal Building and Environment by Elsevier, and of the journals LEUKOS (of the Illuminating Engineering Society) and Buildings and Cities, by Taylor and Francis. She is expert to the Innovation Council of InnoSuisse and Founding member as well as Board member of the Foundation Culture du Bâti (CUB), and is also founding member of the Daylight Academy and an active member of several committees of the Illuminating Engineering Society (IES) and International Commission on Illumination (CIE).
Volkan CevherVolkan Cevher received the B.Sc. (valedictorian) in electrical engineering from Bilkent University in Ankara, Turkey, in 1999 and the Ph.D. in electrical and computer engineering from the Georgia Institute of Technology in Atlanta, GA in 2005. He was a Research Scientist with the University of Maryland, College Park from 2006-2007 and also with Rice University in Houston, TX, from 2008-2009. Currently, he is an Associate Professor at the Swiss Federal Institute of Technology Lausanne and a Faculty Fellow in the Electrical and Computer Engineering Department at Rice University. His research interests include machine learning, signal processing theory, optimization theory and methods, and information theory. Dr. Cevher is an ELLIS fellow and was the recipient of the Google Faculty Research award in 2018, the IEEE Signal Processing Society Best Paper Award in 2016, a Best Paper Award at CAMSAP in 2015, a Best Paper Award at SPARS in 2009, and an ERC CG in 2016 as well as an ERC StG in 2011.
Anton SchleissProf. Dr. Anton J. Schleiss graduated in Civil Engineering from the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland, in 1978. After joining the Laboratory of Hydraulic, Hydrology and Glaciology at ETH as a research associate and senior assistant, he obtained a Doctorate of Technical Sciences on the topic of pressure tunnel design in 1986. After that he worked for 11 years for Electrowatt Engineering Ltd. (now Pöyry) in Zurich and was involved in the design of many hydropower projects around the world as an expert on hydraulic engineering and underground waterways. Until 1996 he was Head of the Hydraulic Structures Section in the Hydropower Department at Electrowatt. In 1997, he was nominated full professor and became Director of the Laboratory of Hydraulic Constructions (LCH) in the Civil Engineering Department of the Swiss Federal Institute of Technology Lausanne (EPFL). The LCH activities comprise education, research and services in the field of both fundamental and applied hydraulics and design of hydraulic structures and schemes. The research focuses on the interaction between water, sediment-rock, air and hydraulic structures as well as associated environmental issues and involves both numerical and physical modeling of water infrastructures. In May 2018, he became Honorary Professor at EPFL. More than 50 PhD and Postdoc research projects have been carried out under his guidance. From 1999 to 2009 he was Director of the Master of Advanced Studies (MAS) in Water Resources Management and Hydraulic Engineering held in Lausanne in collaboration with ETH Zurich and the universities of Innsbruck (Austria), Munich (Germany), Grenoble (France) and Liège (Belgium). From 2006 to 2012 he was the Head of the Civil Engineering program of EPFL and chairman of the Swiss Committee on Dams (SwissCOLD). In 2006, he obtained the ASCE Karl Emil Hilgard Hydraulic Price as well as the J. C. Stevens Award. He was listed in 2011 among the 20 international personalities that “have made the biggest difference to the sector Water Power & Dam Construction over the last 10 years”. Between 2014 and 2017 he was Council member of International Association for Hydro-Environment Engineering and Research (IAHR) and he was chair of the Europe Regional Division of IAHR until 2016. For his outstanding contributions to advance the art and science of hydraulic structures engineering he obtained in 2015 the ASCE-EWRI Hydraulic Structures Medal. The French Hydro Society (SHF) awarded him with the Grand Prix SHF 2018. After having served as vice-president between 2012 and 2015 he was president of the International Commission on Large Dams (ICOLD) from 2015 to 2018. On behalf of ICOLD he his the coordinator of the EU Horizon 2020 project "Hydropower Europe". With more than 40 years of experience he is regularly involved as a consultant and expert in large water infrastructures projects including hydropower and dams all over the world. Awards (besides those mentioned above): ASCE-Journal of Hydraulic Engineering Outstanding Reviewer Recognition 2013 ASCE-EWRI-Journal of Hydraulic Engineering 2014 Best Technical Note
Vassily HatzimanikatisDr. Vassily Hatzimanikatis is currently Associate Professor of Chemical Engineering and Bioengineering at Ecole Polytechnique Federale de Lausanne (EPFL), in Lausanne, Switzerland. Vassily received a PhD and an MS in Chemical Engineering from the California Institute of Technology, and his Diploma in Chemical Engineering from the University of Patras, in Greece. After the completion of his doctoral studies, he held a research group leader position at the Swiss Federal Institute of Technology in Zurich (ETHZ), Switzerland. Prior to joining EPFL, Vassily worked for three years in DuPont, Cargill, and Cargill Dow, and he has been assistant professor at Northwestern University, at Illinois, USA.
Vassilys research interests are in the areas of computational systems biology, biotechnology, and complexity. He is associate editor of the journals Biotechnology & Bioengineering, Metabolic Engineering and Integrative Biology, and he serves on the editorial advisory board of the journals Bioprocess and Biosystems Engineering, Journal of Chemical Technology and Biotechnology, and Industrial Biotechnology. He has written over 70 technical publications and he is co-inventor in three patents and patent applications.
Vassily is a fellow of the American Institute for Medical and Biological Engineering (2010), he was a DuPont Young Professor (2001-2004), and he has also received the Jay Bailey Young Investigator Award in Metabolic Engineering (2000), and the ACS Elmar Gaden Award (2011).
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
