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Explores how inflammation promotes tumor growth and immunosuppression, focusing on the role of inflammatory cells like MDSCs and neutrophils in the tumor microenvironment.
Explores molecular glues as new drug modalities, focusing on binding forces, energetics, biomolecular interactions, quantification, drug development, and structural characterization.
Covers the design and analysis of inhibitors for next-generation covalent drugs, focusing on target engagement and the importance of cysteine targeting.
Delves into identifying drug targets, ensuring efficacy, and maintaining safety in medical chemistry, covering genetic tests, chirality, stereochemistry, drug resistance, and drug-likeness rules.
Explores precision oncology, focusing on predictive biomarkers, big data analysis, NGS applications, immune response mechanisms, and the personalization of immuno-oncology.
Delves into enzyme inhibition, reversible and irreversible binding, and covalent drugs, exploring drug modes of action and their impact on drug efficacy.
