Concept

Ciliary neurotrophic factor

Related publications (33)

Treatment of amyotrophic lateral sclerosis using a gene therapy approach

Neurotrophic factors which act on motor neurons may provide an efficient treatment for amyotrophic lateral sclerosis. In order to overcome the difficulty of administering proteins into the central nervous system, it is possible to use a gene therapy approa ...

1995

Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones

Patrick Aebischer

Glial cell line-derived neurotrophic factor (GDNF) has been postulated to be a specific dopaminergic neurotrophic factor since it selectively enhances the survival of dopaminergic neurones in vitro. We report here that GDNF can also act as a neurotrophic f ...

1994

Primary structure and biological activity of human brain-derived neurotrophic factor

Florian Maria Wurm

Brain-derived neurotrophic factor (BDNF) is a 27-kDa basic protein of noncovalently linked 13.5-kD subunits related to nerve growth factor and is produced by the central nervous system (CNS). BDNF has been shown to promote the survival of neurons located i ...

1991

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