Concept

Therapeutic drug monitoring

Related publications (32)

Biofunctional Scaffold Design for Soft Tissue Regeneration

Fibrin has long been used clinically for hemostasis and sealing and has been extensively characterized as a biomaterial. Yet, in terms of harnessing its potential for use in tissue regeneration, there remains a wide gap between in vitro experimentation and ...

EPFL2011

Nano-Sensor and Circuit Design for Anti-Cancer Drug Detection

Giovanni De Micheli, Sandro Carrara, Camilla Baj-Rossi, Seyedeh Sara Ghoreishizadeh

The development of new technologies to monitor drugs concentration directly in patient’s blood is absolutely required to succeed in personalized drug therapies. In this study, Etoposide - a well-known anti-cancer drug - has been chosen as model for cyclic ...

2011

It is All About Proteases: From Drug Delivery to In Vivo Imaging and Photomedicine

Hubert van den Bergh

Clinical studies provide overwhelming evidence for the importance of proteolytic imbalance and the upregulation of diverse protease classes in diseases such as cancer and arthritis. While the complex nature of proteolytic networks has hampered the developm ...

Bentham Science Publishers2011

Example-based Support Vector Machine for Drug Concentration Analysis

Giovanni De Micheli, Wenqi You Dubout

Machine learning has been largely applied to ana- lyze data in various domains, but it is still new to personalized medicine, especially dose individualization. In this paper, we focus on the prediction of drug concentrations using Support Vector Machines ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2011

Chemistry and Biology of Natural Products

Jean-Yves Wach

This thesis is divided in four independent parts related to four different research projects. Each chapter describes one of the multiple aspects covered by organic chemistry, such as the generation of functional interfaces, understanding of biological proc ...

EPFL2011

Evaluating the use phase energy requirements of a machine tool system

Paul Xirouchakis

This paper has an energy consumption reduction perspective by considering alternative machining strategies and system components interactions translated into variable and constant power flows with respect to various use phase regimes of a machine tool syst ...

Elsevier2011

DCE-MRI data analysis for cancer area classification

Alessandro Daducci

OBJECTIVES: The paper aims at improving the support of medical researchers in the context of in-vivo cancer imaging. Morphological and functional parameters obtained by dynamic contrast-enhanced MRI (DCE-MRI) techniques are analyzed, which aim at investiga ...

Schattauer2009

Laser-based plasma diagnostics for PECVD of silicon thin films

Christophe Ballif, Andrea Feltrin, Benjamin Strahm

We present two laser systems to monitor plasma conditions in a plasma-enhanced chemical vapor deposition chamber. The first optical system is a high-resolution quantum cascade laser-based infrared absorption spectrometer designed to measure the input silan ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2009

Synthèse, structure et propriétés physicochimiques des cyclosporines

Olivier Turpin

Cyclosporin is a cyclic undecapeptide useful as drug for organ transplantation due to its immunosuppressive properties. Ten years ago, an anti-viral activity was discovered, incompatible with immunosuppression. These two activities originate in the presenc ...

EPFL2004

Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection

Jacques Fellay, Amalio Telenti, Thierry Buclin

The reverse transcriptase inhibitor efavirenz is currently used at a fixed dose of 600 mg/d. However, dosage individualization based on plasma concentration monitoring might be indicated. This study aimed to assess the efavirenz pharmacokinetic profile and ...

Elsevier2003

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