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Purpose: Choroidal melanoma is the most common primary malignant ocular tumor in human adults. Relevant mouse models of human uveal melanoma still remain to be developed. We have studied the transgenic mouse strain, Tyrp-1-TAg, to try to gain insight into ...
In mammals, the melanin pigment is produced in two cell types of distinct developmental origins. The melanocytes of the skin originate form the neural crest whereas the retinal pigment epithelium (RPE) of the eye originates from the optic cup. The genetic ...
To study the relationship among tyrosinase activity, melanin production, and the routing of retinal ganglion cell (RGC) axons at the optic chiasm, we analysed mice with varying doses of the tyrosinase gene. These include the dark-eyed albino (Tyrc44H), a r ...
The tyrosinase family comprises three members, tyrosinase (Tyr), tyrosinase-related protein 1 (Tyrp1), and dopachrome tautomerase (Dct). Null mutations and deletions at the Tyr and Tyrp1 loci are known and phenotypically affect coat color due to the absenc ...
A parallel Frequency Domain Optical Coherence Tomography (FD-OCT) system and - to the best of our knowledge- first in vivo tomograms obtained with such system are presented. A full tomogram of 256(x) x 512(z) pixels covering a sample region of 8 mm x 3,8 m ...
The albino mouse was already known in ancient times and was apparently selectively bred in Egypt, China, and Japan. Thus, it is not surprising that the c or albino locus (now the Tyr locus) was among the first used to demonstrate Mendelian inheritance in m ...
It is well-known that taking portrait photographs with a built in camera may create a red-eye effect. This effect is caused by the light entering the subject’s eye through the pupil and reflecting from the retina back to the sensor. These red eyes are prob ...
This paper presents a novel method of enhancing image quality of face pictures using 3D and spectral information. Most conventional techniques directly work on the image data, shifting the skin color to a predefined skin tone, and so do not take into accou ...
Images of a scene captured with multiple cameras will have different color values due to variations in capture and color rendering across devices. We present a method to accurately retrieve color information from uncalibrated images taken under uncontrolle ...
Images of a scene captured with multiple cameras will have different color values due to variations in color rendering across devices. We present a method to accurately retrieve color information from uncalibrated images taken under uncontrolled lighting c ...
