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The aim of this principally experimental study is to understand from fluid mechanic principles why an insignificant anesthetic dose administered as a short bolus into the cerebrospinal fluid inside the subarachnoid space provides greater pain relief than a ...
X-linked adrenoleukodystrophy (X-ALD) is the most common inherited peroxisomal disorder characterized by a progressive demyelination of the central nervous system. The marked loss of myelin and oligodendrocytes observed in the disease prompted us to evalua ...
The invention relates to a viscosimetric sensor for monitoring an analyte level in a patient or in body fluids ex vivo. In particular, the invention relates to a sensor for monitoring analytes, such as glucose levels in a patient. The sensor comprises at l ...
A virtual reality system for the training of the lumbar puncture intervention is presented. We use a haptic device with six degrees of freedom (6DOF) to feedback forces that resist needle insertion and rotation. An improved haptic volume rendering approach ...
It has been established that primary stability of femoral stems is a determinant of the clinical success of cementless total hip arthroplasty[1]. Excessive interface micromotions may lead to a peri-implant fibrous tissue formation resulting in aseptic loos ...
A photoacoustic (PA) sensor has been developed to monitor hydrogen chloride at sub-ppm level in the 1740-nm region. The system was designed to control the process in the novel low-water-peak optical fiber manufacturing process. Relaxation effects in hydrog ...
Micromotion affects the tissue outcome at the peri-implant site. Interstitial fluid flow, induced by micromotion, may play a curtail part in the mesenchymal stem cell differentiation pathway necessary for bone regeneration. The aim of this project is to mo ...
The hematopoietic system is a regenerative tissue with high cell turnover. Normal homeostasis of the hematopoietic system is insured by hematopoietic stem cells (HSCs). The important features of HSCs are the capacity to self-renew and multipotency. Multipo ...
Cerebral vasospasm is a typical complication occurring after Subarachnoid Hemorrhage, which may
lead to delayed cerebral ischemia and death. The standard method to detect vasospasm is
angiography, which is an invasive procedure. Monitoring of vasospasm i ...
Severe lesions of the rodent or human spinal cord lead to permanent paralysis of the legs. Here, we review novel evidences suggesting that interventions combining pharmacological and electrical stimulations of the spinal cord have a high potential to promo ...