Concept
Demyelinating disease
Related publications (49)
Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes
Tobias Kober, Tom Hilbert, Gian Franco Piredda
BACKGROUND AND PURPOSE: MS lesions exhibit varying degrees of axonal and myelin damage. A comprehensive description of lesion phenotypes could contribute to an improved radiologic evaluation of smoldering inflammation and remyelination processes. This stud ...
Amer Soc Neuroradiology2024Comprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their extracellular vesicles
Alexey Sapozhnik, Samuel Jones
JC polyomavirus (JCPyV) is an opportunistic virus that remains in a latent state in the kidneys and lymphoid organs of more than half of the human adult population. In rare cases of severe immune suppression, the virus is able to establish a lytic infectio ...
Washington2023Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues
Jean-Philippe Thiran, Meritxell Bach Cuadra, Tobias Kober, Cristina Granziera, Francesco La Rosa, Maxence Charles F Wynen
The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to misdiagnosis, which remains an issue in present-day clinical practice. In addition, conventional biomarkers only moderately correlate with MS disease progres ...
ELSEVIER SCI LTD2022Challenges for biophysical modeling of microstructure
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25 years. In this review, we dwell on the various challenges along the journey of bringing a biophysical model from initial design to clinical implementation, identifyi ...
2020