Concept

Flux (metabolism)

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Flux (metabolism)

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Discovery of novel competitive dihydropteridine reductase inhibitors via high throughput screening and their effect on metabolic pterin balance of fibroblast.

Deciphering ambiguous control over fluxes through characterization and reduction of uncertainty

redGEM: Systematic reduction and analysis of genome-scale metabolic reconstructions for development of consistent core metabolic models

Thermodynamics-based Metabolite Sensitivity Analysis in metabolic networks

Understanding reprogramming of cancer cell metabolism using metabolic modeling

Identification of the enzymes that determine the robustness of lipid profiles in yeast

Cytosolic Proteostasis Networks of the Mitochondrial Stress Response

In vivo cerebral metabolism of glioblastoma xenografts assessed with ¹H MRS, ¹³C MRS and ¹⁸F-FDG PET

Reconstruction of biological pathways and metabolic networks from in silico labeled metabolites

EXPLORING CHEMODIVERSITY IN METABOLISM TOWARDS THE SUPERVISED INTEGRATION OF CHEMISTRY INTO BIOLOGY