Concept

Granulomatosis with polyangiitis

Related publications (5)

Targeting the aging of tumor-associated neutrophils in lung cancer

Neutrophils are leukocytes that play a key role in innate immunity. Their mode of action in case of infection is well described, but their impact in different chronic diseases, such as cancer, remains unclear. Nevertheless, recent publications describe neu ...

EPFL2024

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

Andrea Ablasser

Kessler et al. identify aberrant DNA recognition by cGAS/STING and IFN-I production by inflammatory macrophages as a driver of severe ANCA-associated vasculitis. Pharmacological interventions blocking this pathway ameliorate disease and accelerate recovery ...

ROCKEFELLER UNIV PRESS2022

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

Stewart Cole

During active TB in humans a spectrum of pulmonary granulomas with central necrosis and hypoxia exists. BALB/c mice, predominantly used in TB drug development, do not reproduce this complex pathology thereby inaccurately predicting clinical outcome. We fou ...

Nature Publishing Group2017

Gold nanoparticles as high-resolution X-ray imaging contrast agents for the analysis of tumor-related micro-vasculature

Giorgio Margaritondo

Background: Angiogenesis is widely investigated in conjunction with cancer development, in particular because of the possibility of early stage detection and of new therapeutic strategies. However, such studies are negatively affected by the limitations of ...

BioMed Central2012

Mechanical and electronic properties of vanadium oxide nanotubes

László Forró, Arnaud Magrez, Andras Kis, Balazs Sipos, Jin Won Seo, Martial Duchamp, Neven Barisic

Vanadium oxide nanotubes with a diameter of 20-100 nm and an aspect ratio of 50-100 were synthesized by hydrothermal method. Young's modulus of 20-80 GPa was obtained by bending measurements of individual nanotubes using an atomic force microscope. Electri ...

American Institute of Physics2009

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