Concept

Sucrose intolerance

Summary
Sucrose intolerance or genetic sucrase-isomaltase deficiency (GSID) is the condition in which sucrase-isomaltase, an enzyme needed for proper metabolism of sucrose (sugar) and starch (e.g., grains), is not produced or the enzyme produced is either partially functional or non-functional in the small intestine. All GSID patients lack fully functional sucrase, while the isomaltase activity can vary from minimal functionality to almost normal activity. The presence of residual isomaltase activity may explain why some GSID patients are better able to tolerate starch in their diet than others with GSID. Signs and symptoms *Abdominal cramps and bloating *Diarrhea and constipation *Vomiting *Hypoglycemia and headaches *Poor weight gain and growth *Upper respiratory tract and viral diseases *Anxiety and heart palpitations *Excess gas production Cause Sucrose intolerance can be caused by genetic mutations in which both parents must contain this gene for the child to carry th
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