Concept

Nicole Marthe Le Douarin

Summary
Nicole Marthe Le Douarin (born 20 August 1930) is a developmental biologist known for her studies of chimeras, which have led to critical insights regarding higher animal nervous and immune systems. Le Douarin invented an embryo manipulation technology to produce chimeric embryos, from chicken and quails. Her research has shed light on the development of higher animal nervous and immune systems. She showed that precursor cells within the neural crest were multipotent. Her technique has also permitted her to shed light on the development of the blood and immune systems. Her work on antero-posterior patterning of the vertebrate digestive tract laid the grounds for future work, leading to a better understanding of antero-posterior patterning in the digestive tract. Early years and education Le Douarin was born on 20 August 1930 in Lorient, France. She was an only child, raised by both parents in the town of Lorient, where her mother worked as a schoolteacher and her father a
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