Concept
Critical period hypothesis
Related publications (47)
Molecular mechanism of plasmid elimination by the DdmDE defense system
Melanie Blokesch, Sandrine Stutzmann, David William Adams, Laurie Righi
Seventh pandemic Vibrio cholerae strains contain two pathogenicity islands that encode the DNA defense modules DdmABC and DdmDE. Here we use cryogenic electron microscopy to reveal the mechanistic basis for plasmid defense by DdmDE. A structure of the DdmD ...
2024Me, Myself, and I: Neural Activity for Self versus Other across Development
Solange Noémie Jeanne Denervaud, Paola Zanchi
Although adults and children differ in self-vs.-other perception, a developmental perspective on this discriminative ability at the brain level is missing. This study examined neural activation for self-vs.-other in a sample of 39 participants spanning fou ...
Basel2023The effects of war on Ukrainian research
Gaétan Jean A de Rassenfosse, Wolf-Hendrik Peter Uhlbach, Tetiana Murovana
The ongoing war in Ukraine has profoundly impacted the Ukrainian scientific community. Numerous researchers have either emigrated or transitioned to alternate professions. For those who remain in research, the destruction of civil infrastructure and psycho ...
London2023The critical periods of cerebral plasticity: A key aspect in a dialog between psychoanalysis and neuroscience centered on the psychopathology of schizophrenia
Through research into the molecular and cellular mechanisms that occur during critical periods, recent experimental neurobiological data have brought to light the importance of early childhood. These have demonstrated that childhood and early environmental ...
FRONTIERS MEDIA SA2022Prenatal auditory experience and its sequelae
Lukas Vogelsang, Marin Vogelsang
Towards the end of the second trimester of gestation, a human fetus is able to register environmental sounds. This in utero auditory experience is characterized by comprising strongly low-pass-filtered versions of sounds from the external world. Here, we p ...
WILEY2022Rapid suppression and sustained activation of distinct cortical regions for a delayed sensory-triggered motor response
Wulfram Gerstner, Carl Petersen, Sylvain Crochet, Alireza Modirshanechi, Vahid Esmaeili, Yanqi Liu, Georgios Foustoukos, Samuel Pavio Muscinelli, Keita Tamura, Anastasiia Oryshchuk, Marta Boscaglia
The neuronal mechanisms generating a delayed motor response initiated by a sensory cue remain elusive. Here, we tracked the precise sequence of cortical activity in mice transforming a brief whisker stimulus into delayed licking using wide-field calcium im ...
2021Dysmaturation Observed as Altered Hippocampal Functional Connectivity at Rest Is Associated With the Emergence of Positive Psychotic Symptoms in Patients With 22q11 Deletion Syndrome
Dimitri Nestor Alice Van De Ville, Maude Schneider, Farnaz Delavari, Daniela Maria Zöller, Karin Bortolin
BACKGROUND: Hippocampal alterations are among the most replicated neuroimaging findings across the psychosis spectrum. Moreover, there is strong translational evidence that preserving the maturation of hippocampal networks in mice models prevents the progr ...
ELSEVIER SCIENCE INC2021Probabilistic Symbol Sequence Matching and its Application to Pathological Speech Intelligibility Assessment
Matching of a test signal to a reference word hypothesis forms the core of many speech processing problems, including objective speech intelligibility assessment. This paper first shows that the comparison of two speech signals can be formulated as matchin ...
Idiap2021Band gaps of liquid water and hexagonal ice through advanced electronic-structure calculations
Alfredo Pasquarello, Igor Reshetnyak, Thomas Bischoff
The fundamental band gaps of liquid water and hexagonal ice are calculated through advanced electronicstructure methods. We compare specifically the performance of state-of-the-art GW calculations with nonempirical hybrid functionals. For the latter, we fi ...
AMER PHYSICAL SOC2021Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease
Hilal Lashuel, Magdalena Zweckstetter
With the advent of the genetic era in Parkinson's disease (PD) research in 1997, alpha-synuclein was identified as an important player in a complex neurodegenerative disease that affects >10 million people worldwide. PD has been estimated to have an econom ...
NATURE RESEARCH2021