Publications related to Atheroma

Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Andreas Pitzschke, Manish Jain, Ying Xiao

Although the versatility of photodynamic therapy (PDT) is well established, the technical aspects of light delivery systems vary significantly depending on the targeted organ. This article describes the optical properties of a light and drug delivery syste ...

2020

Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence

Johan Auwerx, Norman Lionel Moullan, Lei Chen

Long noncoding RNAs (lncRNAs) are emerging regulators of biological processes in the vessel wall; however, their role in atherosclerosis remains poorly defined. We used RNA sequencing to profile lncRNAs derived specifically from the aortic intima of Ldlr(- ...

AMER ASSOC ADVANCEMENT SCIENCE2020

An image-based computational hemodynamics study of the Systolic Anterior Motion of the mitral valve

Alfio Quarteroni, Luca Dede', Christian Vergara, Marco Fedele

Systolic Anterior Motion (SAM) of the mitral valve - often associated with Hypertrophic Obstructive Cardiomyopathy (HOCM) - is a cardiac pathology in which a functional subaortic stenosis is induced during systole by the mitral leaflets partially obstructi ...

PERGAMON-ELSEVIER SCIENCE LTD2020

A 1D computer model of the arterial circulation in horses: An important resource for studying global interactions between heart and vessels under normal and pathological conditions

Nikolaos Stergiopoulos, Patrick Segers

Arterial rupture in horses has been observed during exercise, after phenylephrine administration or during parturition (uterine artery). In human pathophysiological research, the use of computer models for studying arterial hemodynamics and understanding n ...

2019

Synchrotron-based phase contrast imaging of cardiovascular tissue in mice-grating interferometry or phase propagation?

Nikolaos Stergiopoulos, Lydia Aslanidou, Bram Trachet, Goran Lovric, Mauro Ferraro, Patrick Segers

Synchrotron-based x-ray phase-contrast imaging allows for detailed 3D insight into the microstructure of soft tissue and is increasingly used to improve our understanding of mouse models of cardiovascular disease. Two techniques dominate the field: grating ...

2019

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Manish Jain

Acute coronary syndrome is a life-threatening condition of utmost clinical importance, which, despite recent progress in the field, is still associated with high morbidity and mortality. Acute coronary syndrome results from a rupture or erosion of vulnerab ...

Wiley2017

Large eddy simulations for blood dynamics in realistic stenotic carotids

Alfio Quarteroni, Christian Vergara

In this paper, we consider large eddy simulations (LES) for human stenotic carotids in presence of atheromasic plaque, a pathological condition where transitional effects to turbulence may occur, with relevant clinical implications such as plaque rupture. ...

Wiley2017

Computational study of the risk of restenosis in coronary bypasses

Alfio Quarteroni, Christian Vergara

Coronary artery disease, caused by the buildup of atherosclerotic plaques in the coronary vessel wall, is one of the leading causes of death in the world. For high-risk patients, coronary artery bypass graft is the preferred treatment. Despite overall exce ...

Springer Heidelberg2017

Alamandine abrogates neutrophil degranulation in atherosclerotic mice

Nikolaos Stergiopoulos, Rodrigo Araujo Fraga Da Silva

Background Neutrophil-mediated inflammation was recently identified as an active contributor to athero-progression. Therapeutic strategies inhibiting neutrophil degranulation or recruitment were hypothesized to positively impact on plaque vulnerability. In ...

Wiley-Blackwell2017

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Atheroma

Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque

Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression

Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence

An image-based computational hemodynamics study of the Systolic Anterior Motion of the mitral valve

A 1D computer model of the arterial circulation in horses: An important resource for studying global interactions between heart and vessels under normal and pathological conditions

Synchrotron-based phase contrast imaging of cardiovascular tissue in mice-grating interferometry or phase propagation?

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?

Large eddy simulations for blood dynamics in realistic stenotic carotids

Computational study of the risk of restenosis in coronary bypasses

Alamandine abrogates neutrophil degranulation in atherosclerotic mice

Graph Chatbot

Chat with Graph Search

Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque

Alamandine abrogates neutrophil degranulation in atherosclerotic mice

Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence

An image-based computational hemodynamics study of the Systolic Anterior Motion of the mitral valve

Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression

A 1D computer model of the arterial circulation in horses: An important resource for studying global interactions between heart and vessels under normal and pathological conditions

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?

Synchrotron-based phase contrast imaging of cardiovascular tissue in mice-grating interferometry or phase propagation?

Computational study of the risk of restenosis in coronary bypasses

Large eddy simulations for blood dynamics in realistic stenotic carotids