Publications related to Major depressive disorder

Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Simone Astori, Ioannis Zalachoras, Mandy Meijer

Individuals frequently differ in their behavioral and cognitive responses to stress. However, whether motivation is differently affected by acute stress in different individuals remains to be established. By exploiting natural variation in trait anxiety in ...

2022

Agency Deficits in a Human Genetic Model of Schizophrenia: Insights From 22q11DS Patients

Olaf Blanke, Maude Schneider, Nathan Quentin Faivre, Roy Salomon, Oliver Alan Kannape, Mariia Kaliuzhna, Henrique Galvan Debarba

Schizophrenia is a chronic and disabling mental illness characterized by a disordered sense of self. Current theories suggest that deficiencies in the sense of control over one’s actions (Sense of Agency, SoA) may underlie some of the symptoms of schizophr ...

2022

Predicting Changes in Depression Severity Using the PSYCHE-D (Prediction of Severity Change-Depression) Model Involving Person-Generated Health Data: Longitudinal Case-Control Observational Study

Martin Jaggi, Mariko Makhmutova

Background: In 2017, an estimated 17.3 million adults in the United States experienced at least one major depressive episode, with 35% of them not receiving any treatment. Underdiagnosis of depression has been attributed to many reasons, including stigma s ...

Toronto2022

New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity

Antoine Timothée Cherix, Jean-René Cardinaux

Depression and obesity are major public health concerns, and there is mounting evidence that they share etiopathophysiological mechanisms. The neurobiological pathways involved in both mood and energy balance regulation are complex, multifactorial and stil ...

FRONTIERS MEDIA SA2022

The shine-through paradigm and the schizophrenia spectrum: a summary

Michael Herzog, Simona Adele Garobbio, Maya Roinishvili, Ophélie Gladys Favrod

In the past 10 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...

2021

Activities, Housing Situation and Other Factors Influencing Psychological Strain Experienced During the First COVID-19 Lockdown in Switzerland

Claudia Rebeca Binder Signer, Livia Bianca Fritz, Anna Pagani, Garance Clément, Ralph Hansmann

Background: The Coronavirus disease 2019 (COVID-19) crisis and the corresponding first nationwide lockdown from mid-March to 10 May 2020 engendered considerable psychological strain among people in Switzerland. This study analyzes determinants of changes i ...

2021

Superior robustness of anomalous non-reciprocal topological edge states

Romain Christophe Rémy Fleury, Zhechen Zhang, Pierre Delplace

Robustness against disorder and defects is a pivotal advantage of topological systems, manifested by the absence of electronic backscattering in the quantum-Hall and spin-Hall effects, and by unidirectional waveguiding in their classical analogues. Two-dim ...

2021

Long-term effects of early treatment with SSRIs on cognition and brain development in individuals with 22q11.2 deletion syndrome

Maude Schneider, Marie Schaer, Karin Bortolin

Cognitive deficits in individuals at risk of psychosis represent a significant challenge for research, as current strategies for symptomatic treatment are often ineffective. Recent studies showed that atypical cognitive development predicts the occurrence ...

SPRINGERNATURE2021

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Major depressive disorder

Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA

Agency Deficits in a Human Genetic Model of Schizophrenia: Insights From 22q11DS Patients

Predicting Changes in Depression Severity Using the PSYCHE-D (Prediction of Severity Change-Depression) Model Involving Person-Generated Health Data: Longitudinal Case-Control Observational Study

New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity

Predicting changes in depression using person-generated health data

The shine-through paradigm and the schizophrenia spectrum: a summary

Activities, Housing Situation and Other Factors Influencing Psychological Strain Experienced During the First COVID-19 Lockdown in Switzerland

Superior robustness of anomalous non-reciprocal topological edge states

Long-term effects of early treatment with SSRIs on cognition and brain development in individuals with 22q11.2 deletion syndrome

Plunge and rebound of a taxi market through COVID-19 lockdown: Lessons learned from Shenzhen, China

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Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA

Long-term effects of early treatment with SSRIs on cognition and brain development in individuals with 22q11.2 deletion syndrome

Predicting changes in depression using person-generated health data

Activities, Housing Situation and Other Factors Influencing Psychological Strain Experienced During the First COVID-19 Lockdown in Switzerland

Superior robustness of anomalous non-reciprocal topological edge states

Plunge and rebound of a taxi market through COVID-19 lockdown: Lessons learned from Shenzhen, China

Agency Deficits in a Human Genetic Model of Schizophrenia: Insights From 22q11DS Patients

New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity

The shine-through paradigm and the schizophrenia spectrum: a summary

Predicting Changes in Depression Severity Using the PSYCHE-D (Prediction of Severity Change-Depression) Model Involving Person-Generated Health Data: Longitudinal Case-Control Observational Study