Concept
Substrate (chemistry)
Related people (22)
Christof Holliger
Originaire d'Adliswil, Christof Holliger est né en 1959. Diplômé de l'ETHZ en biologie en 1984, il mène des travaux de recherche dans le domaine de la microbiologie environnementale à l'Université d'Agriculture de Wageningen (Pays-Bas) où il obtient son doctorat en Science de l'environnement en 1992. En 1992, il retourne en Suisse engagé comme collaborateur scientifique et chef de groupe à l'Institut Fédéral pour l'Aménagement, l'Epuration et la Protection des Eaux (EAWAG) à Kastanienbaum. Il y continue ses recherches sur la déchloruration réductrice, commencées aux Pays-Bas, et dirige des travaux sur la réduction des composés nitroaromatiques, la réduction du fer et la méthanogenèse psychrophile dans les sédiments des lacs. En octobre 1998, il est nommé professeur assistant en biotechnologie environnementale au Département de génie rural de l'EPFL. Ses recherches visent l'application des micro-organismes anaérobies pour le traitement des eaux résiduaires. En novembre 2004, il est nommé professeur associé et devient responsable du laboratoire de biotechnologie environnementale à la Faculté de l'Environnement naturel, architectural et construit. L'utilisation des techniques de la biologie moléculaire pour la caractérisation des communautés microbiennes impliquées dans le biotraitement de l'air, des eaux et des sols pollués est un outil clé dans les différents projets de recherche visants le développement des nouveaux procédés de traitement.
Klaus Kern
Klaus Kern is Professor of Physics at EPFL and Director and Scientific Member at the Max-Planck-Institute for Solid State Research in Stuttgart, Germany. He also is Honorary Professor at the University of Konstanz, Germany. His present research interests are in nanoscale science, quantum technology and in microscopy at the atomic limits of space and time. He holds a chemistry degree and PhD from the University of Bonn and a honorary doctors degree from the University of Aalborg. After his doctoral studies he was staff scientist at the Research Center Jülich and visiting scientist at Bell Laboratories, Murray Hill before joining the Faculty of EPFL in 1991 and the Max-Planck-Society in 1998. Professor Kern has authored and coauthored close to 700 scientific publications, which have received nearly 60‘000 citations. He has served frequently on advisory committees to universities, professional societies and institutions and has received numerous scientific awards and honors, including the 2008 Gottfried-Wilhelm-Leibniz Prize and the 2016 Van‘t Hoff Prize. Prof. Kern has also educated a large number of leading scientists in nanoscale physics and chemistry. During the past twenty-five years he has supervised one hundred PhD students and sixty postdoctoral fellows. Today, more than fifty of his former students and postdocs hold prominent faculty positions at Universities around the world.
Julien Maillard
2011 - present: Research associate at the Laboratory for Environmental Biotechnology (LBE, IIE-ENAC, EPFL)
2007 - 2010: Postdoctoral Fellow at the Laboratory for Environmental Biotechnology (LBE, IIE-ENAC, EPFL)
2005 - 2006: Postdoctoral Fellow at the University of East Anglia (UEA, Norwich, UK)
2000 - 2004: PhD thesis at the Laboratory for Environmental Biotechnology (LBE)
1995 - 2000: B.sc & M.sc at the Swiss Federal Institute for Technology, Zurich (ETHZ)
Johan Auwerx
Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Urs von Stockar
Originaire de Zurich, Urs von Stockar est né en1942. Ingénieur chimiste diplômé de l'EPFZ en 1967, il y est ensuite assistant au Laboratoire de chimie technique et, en 1973, soutient sa thèse couronnée par la médaille d'argent de l'EPFZ.
De 1973 à 1976, il travaille au département de génie chimique de l'Université de Californie. Il y enseigne et participe au développement d'un procédé technique pour la conversion biologique de la cellulose en alcool.
En 1977, il est ingénieur chimiste chez Ciba-Geigy. Fin 1977 il est nommé professeur extraordinaire à l'EPFL. Il dirige l'Institut de génie chimique en 1978/79 et en 1989/90. Il est professeur ordinaire en 1982. En 1982/83 et 1993/95, il dirige le Département de chimie. Son enseignement et sa recherche traitent des opérations de transfert de masse et de la biotechnologie, il s'intéresse également aux questions de bioénergétique et de biothermodynamique. Collaborant avec l'UNIL et l'ISREC, son équipe développe des procédés de fabrication d'anticorps monoclônaux spéciaux, capables de protéger les muqueuses humaines. En 1990 il est nommé professeur associé à l'Université de Genève. Il représente la Suisse dans un groupe d'experts de la Fédération européenne de biotechnologie. Après avoir siégé pendant plusieurs années dans son Comité de direction, il a été nommé président de la Fédération Européenne de Biotechnologie pour la période 1996-97. Depuis 1991, il dirige le Comité de coordination suisse pour la biotechnologie.
Diploma in Chemical Eng.-1967-ETHZ, CH
Ph.D.-1972-ETHZ, CH
Postdoc. Fellow-1973-76-Univ. of California, Berkeley, US
Giorgio Margaritondo
Citizen of the USA and Switzerland, Giorgio Margaritondo was born in Rome, Italy, in 1946. He received the Laurea summa cum laude from the University of Rome in 1969. From 1969 he was an employee of the Italian National Research Council in Rome and Frascati and, in 1975-77, he was at Bell Laboratories in the USA. From 1978 to 1990, he was professor of physics at the University of Wisconsin-Madison in the USA; in 1984 he was nominated associate director for research of the Synchrotron Radiation Center of the same university. In 1990 he was nominated "professeur ordinaire" (full professor) at the EPFL; he directed the Institute of Applied Physics and the Physics Department. He was also a honorary faculty member at Vanderbilt University in Nashville. In 2001 he became Dean of the EPFL Faculty of Basic Sciences. In 2004 he was nominated Provost and he served until 2010, when he became Dean of Continuing Education, until his retirement from the EPFL in 2016 In addition to teaching general physics, his activity concerns the physics of semiconductors and superconductors (electronic states, surfaces and interfaces) and of biological systems; his main experimental techniques are electron spectroscopy and spectromicroscopy, x-ray imaging and scanning near-field microscopy, including experiments with synchrotron light and with free electron lasers. Author of more than 700 scientific publications and 9 books, he was also coordinator in 1995-98 of the scientific division of the Elettra synchrotron in Trieste. In 1997-2003 he was coordinator of the European Commission Round Table on synchrotron radiation, and then became president of the Council of the European Commission Integrated Initiative on Synchrotron and Free Electron Laser Science (IA-SFS and then ELISA), the largest network in the world in this domain. In 2011-15, he was Editor-in-Chief of Journal of Physics D (Applied Physics). He is currently vice-president of the council of the Università della Svizzera Italiana (USI), and president of the Scientific and Technological Committee of the Italian Institute of Technology (IIT). He is Fellow of the American Physical Society and of the American Vacuum Society and Fellow and Chartered Physicist of the Institute of Physics.
Hubert Girault
Education: 1979 - Engineering diploma from Grenoble Institute of Technology. FRANCE. 1982 - PhD- Department of Chemistry, University of Southampton. Thesis entitled : Interfacial studies using drop image processing techniques. Positions : 1982 - 1984 SERC Research Fellow. University of Southampton. 1984 - 1985 CNRS Research Fellow. University of Southampton. 1985 - 1992 Lecturer in Physical Chemistry, University of Edinburgh. 1992 - Professor of Physical Chemistry, Ecole Polytechnique Fédérale de Lausanne. 2011 - 2014 Dean of Bachelor and Master studies Hubert Girault is the author of 2 textbooks, the co-author of about 600 scientific publications with more than 20'000 citations and the co-inventor of more than 15 patents. During his academic career, he has supervised 70 PhD students. 30 alumni of his laboratory are now Professors. Honours: Faraday medal 2006, Royal Society of Chemistry, Fellow of the International Society of Electrochemistry 2007, Reilley Award 2015. Fellow of the Electrochemical Society (USA), Shikata International medal, Polarography Society of Japan. Associate editor of Chemical Science
Matteo Dal Peraro
Matteo Dal Peraro graduated in Physics at the University of Padua in 2000. He obtained his Ph.D. in Biophysics at the International School for Advanced Studies (SISSA, Trieste) in 2004. He then received postdoctoral training at the University of Pennsylvania (Philadelphia) under the guidance of Prof. M. L. Klein. He was nominated Tenure Track Assistant Professor at the EPFL School of Life Sciences in late 2007.
His research at the Laboratory for Biomolecular Modeling (LBM), within the Interfaculty Institute of Bioengineering (IBI), focuses on the multiscale modeling of large macromolecular systems.