Martin VetterliMartin Vetterli was appointed president of EPFL by the Federal Council following a selection process conducted by the ETH Board, which unanimously nominated him.
Professor Vetterli was born on 4 October 1957 in Solothurn and received his elementary and secondary education in Neuchâtel Canton. He earned a Bachelor’s degree in electrical engineering from ETH Zurich (ETHZ) in 1981, a Master’s of Science degree from Stanford University in 1982, and a PhD from EPFL in 1986. Professor Vetterli taught at Columbia University as an assistant and then associate professor. He was subsequently named full professor in the Department of Electrical Engineering and Computer Sciences at the University of California at Berkeley before returning to EPFL as a full professor at the age of 38. He has also taught at ETHZ and Stanford University.
Professor Vetterli has earned numerous national and international awards for his research in electrical engineering, computer science and applied mathematics, including the National Latsis Prize in 1996. He is a fellow of both the Association for Computing Machinery and the Institute of Electrical and Electronics Engineers and a member the US National Academy of Engineering. He has published over 170 articles and three reference works.
Professor Vetterli’s work on the theory of wavelets, which are used in signal processing, is considered to be of major importance by his peers, and his areas of expertise, including image and video compression and self-organized communication systems, are central to the development of new information technologies. As the founding director of the National Centre of Competence in Research on Mobile Information and Communication Systems, Professor Vetterli is a staunch advocate of transdisciplinary research.
Professor Vetterli knows EPFL inside and out. An EPFL graduate himself, he began been teaching at the school in 1995, was vice president for International Affairs and then Institutional Affairs from 2004 to 2011, and served as dean of the School of Computer and Communication Sciences in 2011 and 2012. In addition to his role as president of the National Research Council of the Swiss National Science Foundation, a position he held from 2013 to 2016, he heads the EPFL’s Audiovisual Communications Laboratory (LCAV) since 1995.
Professor Vetterli has supported more than 60 students in Switzerland and the United States in their doctoral work and makes a point of following their highly successful careers, whether it is in the academic or business world.
He is the author of some 50 patents, some of which were the basis for start-ups coming out of his lab, such as Dartfish and Illusonic, while others were sold (e.g. Qualcomm) as successful examples of technology transfer. He actively encourages young researchers to market the results of their work.
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Pierre DillenbourgA former teacher in elementary school, Pierre Dillenbourg graduated in educational science (University of Mons, Belgium). He started his research on learning technologies in 1984. In 1986, he has been on of the first in the world to apply machine learning to develop a self-improving teaching system. He obtained a PhD in computer science from the University of Lancaster (UK), in the domain of artificial intelligence applications for education. He has been assistant professor at the University of Geneva. He joined EPFL in 2002. He has been the director of Center for Research and Support on Learning and its Technologies, then academic director of Center for Digital Education, which implements the MOOC strategy of EPFL (over 2 million registrations). He is full professor in learning technologies in the School of Computer & Communication Sciences, where he is the head of the CHILI Lab: "Computer-Human Interaction for Learning & Instruction ». He is the director of the leading house DUAL-T, which develops technologies for dual vocational education systems (carpenters, florists,...). With EPFL colleagues, he launched in 2017 the Swiss EdTech Collider, an incubator with 80 start-ups in learning technologies. He (co-)-founded 4 start-ups, does consulting missions in the corporate world and joined the board of several companies or institutions. In 2018, he co-founded LEARN, the EPFL Center of Learning Sciences that brings together the local initiatives in educational innovation. He is a fellow of the International Society for Learning Sciences. He currently is the Associate Vice-President for Education at EPFL.
Marilyne AndersenMarilyne Andersen is a Full Professor of Sustainable Construction Technologies and heads the Laboratory of Integrated Performance in Design (LIPID) that she launched in the Fall of 2010. She was Dean of the School of Architecture, Civil and Environmental Engineering (ENAC) at EPFL from 2013 to 2018 and is the Academic Director of the Smart Living Lab in Fribourg. She also co-leads the Student Kreativity and Innovation Laboratory (SKIL) at ENAC. Before joining EPFL as a faculty, she was an Assistant Professor then Associate Professor tenure-track in the Building Technology Group of the MIT School of Architecture and Planning and the Head of the MIT Daylighting Lab that she founded in 2004. She has also been Invited Professor at the Singapore University of Technology and Design in 2019. Marilyne Andersen owns a Master of Science in Physics and specialized in daylighting through her PhD in Building Physics at EPFL in the Solar Energy and Building Physics Laboratory (LESO) and as a Visiting Scholar in the Building Technologies Department of the Lawrence Berkeley National Laboratory in California. Her research lies at the interface between science, engineering and architectural design with a dedicated emphasis on the impact of daylight on building occupants. Focused on questions of comfort, perception and health and their implications on energy considerations, these research efforts aim towards a deeper integration of the design process with daylighting performance and indoor comfort, by reaching out to various fields of science, from chronobiology and neuroscience to psychophysics and computer graphics. She is leveraging this research in practice through OCULIGHT dynamics, a startup company she co-founded, which offers specialized consulting services on daylight performance and its psycho-physiological effects on building occupants. She is the author of more than 200 papers published in peer-reviewed journals and international conferences and the recipient of several grants and awards including: the Daylight Award for Research (2016), eleven publication awards and distinctions (2009, 2011, 2012, 2015, 2018, 2019) including the Taylor Technical Talent Award 2009 granted by the Illuminating Engineering Society, the 3M Non-Tenured Faculty Grant (2009), the Mitsui Career Development Professorship at MIT (2008) and the EPFL prize of the Chorafas Foundation awarded to her PhD thesis in Sustainability (2005). Her research or teaching has been supported by professional, institutional and industrial organizations such as: the Swiss and the U.S. National Science Foundations, the Velux Foundation, the European Horizon 2020 program, the Boston Society of Architects, the MIT Energy Initiative and InnoSuisse. She was the leader and faculty advisor of the Swiss Team and its NeighborHub project, who won the U.S. Solar Decathlon 2017 competition with 8 podiums out of 10 contests. She is a member of the Board of the LafargeHolcim Foundation for Sustainable Construction and Head of its Academic Committee. She is also a member of the Editorial Board of the journal Building and Environment by Elsevier, and of the journals LEUKOS (of the Illuminating Engineering Society) and Buildings and Cities, by Taylor and Francis. She is expert to the Innovation Council of InnoSuisse and Founding member as well as Board member of the Foundation Culture du Bâti (CUB), and is also founding member of the Daylight Academy and an active member of several committees of the Illuminating Engineering Society (IES) and International Commission on Illumination (CIE).
Anthony Christopher DavisonAnthony Davison has published on a wide range of topics in statistical theory and methods, and on environmental, biological and financial applications. His main research interests are statistics of extremes, likelihood asymptotics, bootstrap and other resampling methods, and statistical modelling, with a particular focus on the first currently. Statistics of extremes concerns rare events such as storms, high winds and tides, extreme pollution episodes, sporting records, and the like. The subject has a long history, but under the impact of engineering and environmental problems has been an area of intense development in the past 20 years. Davison''s PhD work was in this area, in a project joint between the Departments of Mathematics and Mechanical Engineering at Imperial College, with the aim of modelling potential high exposures to radioactivity due to releases from nuclear installations. The key tools developed, joint with Richard Smith, were regression models for exceedances over high thresholds, which generalized earlier work by hydrologists, and formed the basis of some important later developments. This has led to an ongoing interest in extremes, and in particular their application to environmental and financial data. A major current interest is the development of suitable methods for modelling rare spatio-temporal events, particularly but not only in the context of climate change. Likelihood asymptotics too have undergone very substantial development since 1980. Key tools here have been saddlepoint and related approximations, which can give remarkably accurate approximate distribution and density functions even for very small sample sizes. These approximations can be used for wide classes of parametric models, but also for certain bootstrap and resampling problems. The literature on these methods can seem arcane, but they are potentially widely applicable, and Davison wrote a book joint with Nancy Reid and Alessandra Brazzale intended to promote their use in applications. Bootstrap methods are now used in many areas of application, where they can provide a researcher with accurate inferences tailor-made to the data available, rather than relying on large-sample or other approximations of doubtful validity. The key idea is to replace analytical calculations of biases, variances, confidence and prediction intervals, and other measures of uncertainty with computer simulation from a suitable statistical model. In a nonparametric situation this model consists of the data themselves, and the simulation simply involves resampling from the existing data, while in a parametric case it involves simulation from a suitable parametric model. There is a wide range of possibilities between these extremes, and the book by Davison and Hinkley explores these for many data examples, with the aim of showing how and when resampling methods succeed and why they can fail. He was Editor of Biometrika (2008-2017), Joint Editor of Journal of the Royal Statistical Society, series B (2000-2003), editor of the IMS Lecture Notes Monograph Series (2007), Associate Editor of Biometrika (1987-1999), and Associate Editor of the Brazilian Journal of Probability and Statistics (1987 2006). Currently he on the editorial board of Annual Reviews of Statistics and its Applications. He has served on committees of Royal Statistical Society and of the Institute of Mathematical Statistics. He is an elected Fellow of the American Statistical Assocation and of the Institute of Mathematical Statistics, an elected member of the International Statistical Institute, and a Chartered Statistician. In 2009 he was awarded a laurea honoris causa in Statistical Science by the University of Padova, in 2011 he held a Francqui Chair at Hasselt University, and in 2012 he was Mitchell Lecturer at the University of Glasgow. In 2015 he received the Guy Medal in Silver of the Royal Statistical Society and in 2018 was a Medallion Lecturer of the Institute of Mathematical Statistics.
