Publications related to Alkaline phosphatase

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

Cristina Ramona Cudalbu, Jocelin Grosse, Katarzyna Pierzchala, Veronika Rackayová

Background & Aims: The sequence of events in hepatic encephalopathy (HE) remains unclear. Using the advantages of in vivo 1H-MRS (9.4T) we aimed to analyse the time-course of disease in an established model of type C HE by analysing the longitudinal change ...

2019

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

Rolf Gruetter, Cristina Ramona Cudalbu, Dmitri Firsov, Hikari Ananda Infinity Yoshihara

Detoxification of ammonia by the urea cycle and maintenance of glucose homeostasis by gluconeogenesis are two critical functions of the liver. The bile duct ligation (BDL) model of cirrhosis was used to test the ability of hyperpolarized [6-13C]arginine an ...

2018

(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism

Cristina Ramona Cudalbu, Bernard Lanz, Veronika Rackayová, Corina Mihaela Berset

Chronic liver disease (CLD) leads to a spectrum of neuropsychiatric disorders named hepatic encephalopathy (HE). Even though brain energy metabolism is believed to be altered in chronic HE, few studies have explored energy metabolism in CLD-induced HE, and ...

Springer Verlag2016

Multigene expression in stable CHO cell pools generated with the piggyBac transposon system

Florian Maria Wurm, David Hacker, Sowmya Balasubramanian

Heterogenous populations of recombinant cells (cell pools) stably expressing 1-4 transgenes were generated from Chinese hamster overy (CHO) cells with the piggyBac (PB) transposon system. The cell pools produced different combinations of three model protei ...

American Chemical Society2016

Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice

Jutta Christine Wandrey, Redouan Mahou, Yannick Müller

Background & Aims: Mesenchymal stem cell (MSC) transplantation was shown to be effective for the treatment of liver fibrosis, but the mechanisms of action are not yet fully understood. We transplanted encapsulated human MSCs in two mouse models of liver fi ...

Elsevier Science Bv2015

Characterization of bone progenitor cells after GFP lentivirus transfection

Axelle Deirdre Eve Justafré, Tanja Cloé Hausherr

Several treatments have been developed for treating bone fractures as they are very common events. Amongst other new strategies, synthetic bone substitutes present a very high potential therapy because they lower the risk of infection and rejection. Moreov ...

2015

PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis

Johan Auwerx, Jiujiu Yu

We report the engineering and characterization of paraoxonase-3 knockout mice (Pon3KO). The mice were generally healthy but exhibited quantitative alterations in bile acid metabolism and a 37% increased body weight compared to the wild-type mice on a high ...

Federation of American Society of Experimental Biology2015

Hepatotoxicity induced by neonatal exposure to diethylstilbestrol is maintained throughout adulthood via the nuclear receptor SHP

Kristina Schoonjans

Background: Liver physiology is sensitive to estrogens, which suggests that the liver might be a target of estrogenic endocrine disrupters (EED). However, the long-term consequences of neonatal exposure to EED on liver physiology have rarely been studied. ...

Informa Healthcare2014

Effect of TiO2 Nanoparticles and UV Radiation on Extracellular Enzyme Activity of Intact Heterotrophic Biofilms

Kristin Schirmer, Laura Sigg, Hannah Inka Schug

When introduced into the aquatic environment, TiO2 NP are likely to settle from the water column, which results in increased exposure of benthic communities. Here, we show that the activity of two extracellular enzymes of intact heterotrophic biofilms, bet ...

Amer Chemical Soc2014

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Alkaline phosphatase

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

Brain metabolism during Chronic Hepatic Encephalopathy studied by in vivo 1H and 31P MRS

(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism

Multigene expression in stable CHO cell pools generated with the piggyBac transposon system

Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice

Characterization of bone progenitor cells after GFP lentivirus transfection

PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis

Hepatotoxicity induced by neonatal exposure to diethylstilbestrol is maintained throughout adulthood via the nuclear receptor SHP

Effect of TiO2 Nanoparticles and UV Radiation on Extracellular Enzyme Activity of Intact Heterotrophic Biofilms

Graph Chatbot

Chat with Graph Search

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

Brain metabolism during Chronic Hepatic Encephalopathy studied by in vivo 1H and 31P MRS

(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolism

Multigene expression in stable CHO cell pools generated with the piggyBac transposon system

Characterization of bone progenitor cells after GFP lentivirus transfection

PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis

Hepatotoxicity induced by neonatal exposure to diethylstilbestrol is maintained throughout adulthood via the nuclear receptor SHP

Effect of TiO2 Nanoparticles and UV Radiation on Extracellular Enzyme Activity of Intact Heterotrophic Biofilms