Concept
Drosophila
Related publications (137)
Trio preserves motor synapses and prolongs motor ability during aging
Evelyne Ruchti, Brian Donal McCabe, Soumya Banerjee, Greta Limoni, Samuel William Vernon, Wei Jiao
The decline of motor ability is a hallmark feature of aging and is accompanied by degeneration of motor synaptic terminals. Consistent with this, Drosophila motor synapses undergo characteristic age -dependent structural fragmentation co -incident with dim ...
Cell Press2024The role of the NF-kappaB pathway in Amyotrophic lateral sclerosis pathogenesis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative motor disorder, which results in death within a few years of diagnosis. While the cause of most cases of ALS is unknown, 10% of cases are familial (fALS), and associated with mutations in one of ov ...
EPFL2023Fluid-structure interactions of bristled wings: the trade-off between weight and drag
Pedro Miguel Nunes Pereira de Almeida Reis, Matteo Pezzulla, Yuexia Luna Lin
The smallest flying insects often have bristled wings resembling feathers or combs. We combined experiments and three-dimensional numerical simulations to investigate the trade-off between wing weight and drag generation. In experiments of bristled strips, ...
London2023Centromere structure and function: lessons from Drosophila
The fruit fly Drosophila melanogaster serves as a powerful model organism for advancing our understanding of biological processes, not just by studying its similarities with other organisms including ourselves but also by investigating its differences to u ...
Bethesda2023