Publications related to Rosalind Franklin

Hyperplectonemes: A Higher Order Compact and Dynamic DNA Self-Organization

Giovanni Dietler, Paolo De Los Rios, Giovanni Longo, Fabrizio Benedetti, Aleksandre Japaridze

Bacterial chromosome has a compact structure that dynamically changes its shape in response to bacterial growth rate and growth phase. Determining how chromatin remains accessible to DNA binding proteins, and transcription machinery is crucial to understan ...

American Chemical Society2017

Influence of DNA Binding Dyes on Bare DNA Structure Studied with Atomic Force Microscopy

Giovanni Dietler, Aleksandr Benke, Aleksandre Japaridze, Sylvain Renevey

Fluorescent dyes are widely used for staining and visualization of DNA in optical microscopy based methods. Even though for some dyes the mechanism of binding is known, how this binding affects DNA remains poorly understood. Here we present a novel experim ...

American Chemical Society2015

Structure and Biophysical Properties of a Triple-Stranded Beta-Helix Comprising the Central Spike of Bacteriophage T4

Laure Menin, Petr Leiman, Sergii Buth

Gene product 5 (gp5) of bacteriophage T4 is a spike-shaped protein that functions to disrupt the membrane of the target cell during phage infection. Its C-terminal domain is a long and slender -helix that is formed by three polypeptide chains wrapped aroun ...

Mdpi Ag2015

X-ray structure of the mouse serotonin 5-HT3 receptor

Horst Vogel, Henning Paul-Julius Stahlberg, Rudolf Hovius, Cédric Deluz, Luigino Grasso, Romain Wyss, Ghérici Hassaïne, Menno Berend Tol

Neurotransmitter-gated ion channels of the Cys-loop receptor family mediate fast neurotransmission throughout the nervous system. The molecular processes of neurotransmitter binding, subsequent opening of the ion channel and ion permeation remain poorly un ...

Nature Publishing Group2014

Analysis of the dynamics and competition for resources in the system of protein translation using stochastic simulations

Vassily Hatzimanikatis, Julien Racle, Joana Raquel Pinto Vieira

Protein synthesis plays an important role in biological systems since its products, proteins and enzymes, constitute most of the molecular machinery required for cell regulation, growth and function in the tissue. Understanding the mechanisms of decoding a ...

2013

Fine DNA structure revealed by constant height frequency modulation AFM imaging

Giovanni Dietler, Dusan Vobornik, Andrea Cerreta

Few examples of sub nanometer resolution on biomolecules can be found in literature. In particular, AFM experiments on DNA mostly fail to show the double helical groove periodicity, and so far such a feat was only achieved in liquid. Here we describe a met ...

Elsevier2013

Nanopore Detection of Single Molecule RNAP–DNA Transcription Complex

Aleksandra Radenovic, Erick Antonio Garcia Cordero, Camille Alice Raillon, Floriano Traversi

In the past decade, a number of single-molecule methods have been developed With the aim of investigating single protein and nucleic acid interactions. For the first time we use solid-state nanopore sensing to detect a single E. coli RNAP DNA transcription ...

2012

25 years of recombinant proteins from reactor-grown cells — Where do we go from here?

Florian Maria Wurm, David Hacker

The purpose of this review is to describe the current status and to highlight several emerging trends in the manufacture of recombinant therapeutic proteins in cultivated mammalian cells. focusing on Chinese hamster ovary cells as the major production host ...

Elsevier2009

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Rosalind Franklin

Single-cell studies of Mycobacterium smegmatis cell cycle using time-lapse fluorescence microscopy

Simultaneous preservation of the DNA quality, the community composition and the density of freshwater oligochaetes for the development of genetically based biological indices

Hyperplectonemes: A Higher Order Compact and Dynamic DNA Self-Organization

Influence of DNA Binding Dyes on Bare DNA Structure Studied with Atomic Force Microscopy

Structure and Biophysical Properties of a Triple-Stranded Beta-Helix Comprising the Central Spike of Bacteriophage T4

X-ray structure of the mouse serotonin 5-HT3 receptor

Analysis of the dynamics and competition for resources in the system of protein translation using stochastic simulations

Fine DNA structure revealed by constant height frequency modulation AFM imaging

Nanopore Detection of Single Molecule RNAP–DNA Transcription Complex

25 years of recombinant proteins from reactor-grown cells — Where do we go from here?

Graph Chatbot

Chat with Graph Search

Single-cell studies of Mycobacterium smegmatis cell cycle using time-lapse fluorescence microscopy

Hyperplectonemes: A Higher Order Compact and Dynamic DNA Self-Organization

Fine DNA structure revealed by constant height frequency modulation AFM imaging

Simultaneous preservation of the DNA quality, the community composition and the density of freshwater oligochaetes for the development of genetically based biological indices

Influence of DNA Binding Dyes on Bare DNA Structure Studied with Atomic Force Microscopy

X-ray structure of the mouse serotonin 5-HT3 receptor

Analysis of the dynamics and competition for resources in the system of protein translation using stochastic simulations

25 years of recombinant proteins from reactor-grown cells — Where do we go from here?

Nanopore Detection of Single Molecule RNAP–DNA Transcription Complex

Structure and Biophysical Properties of a Triple-Stranded Beta-Helix Comprising the Central Spike of Bacteriophage T4