Francisco de Orellana Bejarano Pizarro y Torres de Altamirano (fɾanˈθisko ðe oɾeˈʝana; 1511 – November 1546) was a Spanish explorer and conquistador. In one of the most improbably successful voyages in known history, Orellana managed to sail the length of the Amazon, arriving at the river's mouth on 24 August 1542. He and his party sailed along the Atlantic coast until reaching Cubagua Island, near the coast of Venezuela.
Orellana founded the city of Guayaquil in what is now Ecuador, and died during a second expedition on the Amazon.
Born in Trujillo, Caceres (various birth dates, ranging from 1490 to 1511, are still quoted by biographers), Orellana was a close friend and possibly a relative of Francisco Pizarro, the Trujillo-born conquistador of Peru (his cousin, according to some historians). He traveled to the New World (probably in 1527). Orellana served in Nicaragua until joining Pizarro's army in Peru in 1533, where he supported Pizarro in his conflict with Diego de Almagro (1538). After the victory over De Almagro's men, he was appointed governor of La Culata. He re-established the town of Guayaquil, previously founded by Pizarro and repopulated by Sebastián de Belalcázar.
(During the civil war, he sided with the Pizarros and was Ensign General of a force sent by Francisco Pizarro from Lima to aid Hernando Pizarro. He was granted land at Puerto Viejo, on the coast of Ecuador.)
In 1540 Gonzalo Pizarro arrived in Quito as vice governor and was charged by Francisco Pizarro, his older paternal half-brother, with an expedition to locate the "Land of Cinnamon", thought to be somewhere to the east. Orellana was one of Gonzalo Pizarro's lieutenants during his 1541 expedition east of Quito into the South American interior. In Quito, Gonzalo Pizarro collected a force of 220 Spaniards and 4000 natives. At the same time, as second in command, Orellana was sent back to Guayaquil to gather troops and horses. Pizarro left Quito in February 1541, just before Orellana arrived with his 23 men and horses.