Concept

Foreign body reaction

Related publications (44)

In vivo polydopamine coating of Rhodobacter sphaeroides for enhanced electron transfer

Ardemis Anoush Boghossian, Melania Reggente, Fabian Fischer

Recent advances in coupling light-harvesting microorganisms with electronic components have led to a new generation of biohybrid devices based on microbial photocatalysts. These devices are limited by the poorly conductive interface between phototrophs and ...

2024

Radiation Patterns of RF Wireless Devices Implanted in Small Animals: Unexpected Deformations Due to Body Resonance

Anja Skrivervik, Stéphanie Lacour, Zvonimir Sipus, Mingxiang Gao, German Augusto Ramirez Arroyave, Kangling Wu

One challenge in designing RF wireless bioelectronic devices is the impact of the interaction between electromagnetic waves and host body tissues on far-field wireless performance. In this paper, we investigate a peculiar phenomenon of implantable RF wirel ...

2023

A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions

Dominique Pioletti, Peyman Karami, Theofanis Stampoultzis, Yanheng Guo

The drive to develop cartilage implants for the treatment of major defects in the musculoskeletal sys-tem has resulted in a major research thrust towards developing biomaterial devices for cartilage repair. Investigational devices for the restoration of ar ...

ELSEVIER SCI LTD2023

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

Stéphanie Lacour

Fibrotic scarring secondary to the foreign body reaction (FBR) generates a physical barrier obstructing the functional interaction of implantable medical devices with the host tissue. The mechanistic basis of the FBR is poorly understood, restricting the c ...

NATL ACAD SCIENCES2022

Influence of Uncertainty of Body Permittivity on Achievable Radiation Efficiency of Implantable Antennas-Stochastic Analysis

Anja Skrivervik, Zvonimir Sipus

Design of medical sensor implants is very challenging due to numerous restrictions in terms of size and biological acceptability. In addition, large absorption and reflection of electromagnetic waves in body tissues significantly degrades the communication ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Synthesis of branching morphologies

Henry Markram, Lida Kanari

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium for generating model neurons. In one aspect, a method includes receiving a plurality of descriptions of branches of dendrites of one or more neurons and gener ...

2021

Soft Hydrogel Zwitterionic Coatings Minimize Fibroblast and Macrophage Adhesion on Polyimide Substrates

Silvestro Micera, Anna Zahoranova, igor lacik

Minimizing the foreign body reaction to polyimide-based implanted devices plays a pivotal role in several biomedical applications. In this work, we propose materials exhibiting nonbiofouling properties and a Young's modulus reflecting that of soft human ti ...

AMER CHEMICAL SOC2019

Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation

Berna Ayse Özkale Edelmann, Christina Myra Tringides

Mesenchymal stem cell (MSC) therapies demonstrate particular promise in ameliorating diseases of immune dysregulation but are hampered by short in vivo cell persistence and inconsistencies in phenotype. Here, we demonstrate that biomaterial encapsulation i ...

NATL ACAD SCIENCES2019

Development of functionalized alginate-based hydrogels to reduce fibrosis in the transplantation of microencapsulated cells

François Rémi Pierre Noverraz

Nowadays, the development of cell therapy relies mainly on the advances made toward cell microencapsulation which allows to evade the need for immunosuppression during cell transplantation. Among the materials considered for cell encapsulation, hydrogels d ...

EPFL2018

Long-term usability and bio-integration of polyimide-based intraneural stimulating electrodes

Silvestro Micera, Grégoire Courtine, Quentin Barraud, Nawal Noëlle Kinany, Marco Capogrosso, Stanisa Raspopovic, Alessandra Piersigilli, Jacopo Rigosa, Jérôme Gandar, Sophie Marie Marthe Wurth, Polina Shkorbatova, Natalia Pavlova

Stimulation of peripheral nerves has transiently restored lost sensation and has the potential to alleviate motor deficits. However, incomplete characterization of the long-term usability and bio-integration of intra-neural implants has restricted their us ...

Elsevier Sci Ltd2017

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