Concept

Transport protein

Related publications (34)

Steady-state brain glucose transport kinetics re-evaluated with a four-state conformational model

Rolf Gruetter, Hongxia Lei, João Miguel das Neves Duarte, Carole Poitry-Yamate

Glucose supply from blood to brain occurs through facilitative transporter proteins. A near linear relation between brain and plasma glucose has been experimentally determined and described by a reversible model of enzyme kinetics. A conformational four-st ...

Frontiers Research Foundation2009

Studies of blob formation, propagation and transport mechanisms in basic experimental plasmas (TORPEX and CSDX)

Ambrogio Fasoli, Ivo Furno, Benoît Labit, Christian Gabriel Theiler, Stefan Müller

The findings of previous blob studies in the interchange-dominated regime of TORPEX helium (Müller et al 2007 Phys. Plasmas 14 110704) and hydrogen plasmas (Furno et al 2008 Phys. Rev. Lett. 100 055004) are summarized and compared. The onset of blobs is s ...

Institute of Physics2009

Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure

Françoise Gisou van der Goot Grunberg, Xuan Li

The Golgi apparatus consists of a series of flattened cisternal membranes that are aligned in parallel to form stacks. Cytosolic-oriented Golgi-associated proteins have been identified that may coordinate or maintain the Golgi architecture. Here, we descri ...

2007

Lipid-transfer proteins in membrane trafficking at the Golgi complex

Giovanni D'Angelo

The Golgi complex (GC) represents the central junction for membrane trafficking. Protein and lipid cargoes continuously move through the GC in both anterograde and retrograde directions, departing to and arriving from diverse destinations within the cell. ...

2007

Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide

Giovanni D'Angelo

The molecular machinery responsible for the generation of transport carriers moving from the Golgi complex to the plasma membrane relies on a tight interplay between proteins and lipids. Among the lipid-binding proteins of this machinery, we previously ide ...

2007

Interleukin 2 immune response generating formulation, used for treating cancer, comprises IL 2 coupled to transport protein, monoclonal anti IL 2 antibody or monoclonal anti CD 25 antibody

NOVELTY - A formulation comprising one or more components chosen from interleukin (IL)-2 or a derivative thereof coupled to a transport protein, a monoclonal anti-IL-2 antibody, a cancer vaccine based on specific antigens of tumors or tumor growth factors ...

2006

On-chip extrusion of lipid vesicles and tubes through microsized apertures

Philippe Renaud

In this work we present the formation of micrometre-sized lipid vesicles and tubes with perfectly homogeneous diameter and extraordinary length. The method is a novel approach for unconventional fabrication of soft-matter microstructured devices based on t ...

2006

Signaling in morphogenesis: transport cues in morphogenesis

Melody Swartz

Extracellular transport processes play critical roles in morphogenesis. While diffusive transport effects on morphogenesis are well illustrated in examples like blood capillary architecture and in cell morphogenetic responses to the local extracellular pro ...

2003

Xol INXS: role of the liver X and the farnesol X receptors

Johan Auwerx, Kristina Schoonjans

Cholesterol and bile acid metabolism is tightly controlled by nuclear receptors. The liver X receptor, an oxysterol-activated nuclear receptor, limits cholesterol accumulation in the body both by stimulating reverse cholesterol transport and by inhibiting ...

2001

Glycoprotein-associated amino acid exchangers: broadening the range of transport specificity

Lukas Kühn

Members of the newly discovered glycoprotein-associated amino acid transporter family (gpaAT-family) share a similar primary structure with >40% identity, a predicted 12-transmembrane segment topology and the requirement for association with a glycoprot ...

2000

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