Concept

Uridine diphosphate glucose

Related publications (43)

Hepatic glucose sensing and integrative pathways in the liver

Kristina Schoonjans, Maaike Hélène Oosterveer

The hepatic glucose-sensing system is a functional network of enzymes and transcription factors that is critical for the maintenance of energy homeostasis and systemic glycemia. Here we review the recent literature on its components and metabolic actions. ...

Springer Basel Ag2014

Elucidating the role of neuron-astrocyte metabolic coupling in learning and memory

Monika Tadi

The brain has very high energy demands that are mainly met by the circulating blood glucose to ensure its proper functioning. Thus, it is not surprising that though the human brain weighs only 2- 3% of the body weight, it consumes approximately 25% of tota ...

EPFL2013

Increasing the sensitivity of enzyme-based biosensors using copper-chloride and EDTA

Nico de Rooij, Peter Van der Wal, Sara Talaei

The effect of CuCl2 and EDTA on increasing the sensitivity of enzyme biosensors was evaluated. The experiments revealed that successive exposure of these solutions to our biosensors can increase the sensitivity of the glucose and lactate biosensors up to 8 ...

2012

Cell metabolism monitoring using a microfluidic cartridge with enzyme-based microreactors

Nico de Rooij, Peter Van der Wal, Sara Talaei

We present a novel microfluidic approach for on-line analysis of cell metabolism by simultaneous measurement of two important indicators (glucose and lactate) in a small volume (100 µl) of cell-culture medium. The in-vitro study of cell metabolism is espec ...

2012

Measurements of Glycogen Metabolism in the Living Brain

Rolf Gruetter

To maintain brain function, the combustion of glucose for the generation of energy (ATP) is essential, yet the brain maintains fuel storage in the form of glial glycogen. Although brain glycogen levels are lower than those in the liver, they exceed the nor ...

Springer2012

Altered Glycogen Metabolism in Cultured Astrocytes from Mice with Chronic Glutathione Deficit; Relevance for Neuroenergetics in Schizophrenia

Pierre Magistretti, Igor Allaman, Kim Do, Jean-Marie Petit

Neurodegenerative and psychiatric disorders including Alzheimer's, Parkinson's or Huntington's diseases and schizophrenia have been associated with a deficit in glutathione (GSH). In particular, a polymorphism in the gene of glutamate cysteine ligase modul ...

Public Library of Science2011

Comparison of Three Methods of Biocompatible Multi-Walled Carbon Nanotubes Confinement for the Development of Implantable Amperometric Adenosine-5′-Triphosphate Biosensors

Giovanni De Micheli, Sandro Carrara, Andrea Cavallini

An amperometric biosensor for adenosine 5 -triphosphate (ATP) was developed applying a competitive assay of two glucose converting enzymes: glucose oxidase (GOD) and hexokinase (HEX). Competition between GOD and HEX for glucose in presence of ATP, lead to ...

American Scientific Publishers2011

Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes

Pierre Magistretti, Jean-Luc Martin, Igor Allaman

RATIONALE: The pharmacological actions of most antidepressants are ascribed to the modulation of serotonergic and/or noradrenergic transmission in the brain. During therapeutic treatment for major depression, fluoxetine, one of the most commonly prescribed ...

Springer Verlag2011

Metabolic response of the cerebral cortex following gentle sleep deprivation and modafinil administration

Pierre Magistretti, Jean-Marie Petit, Christophe Kopp

Objectives: The main energy reserve of the brain is glycogen, which is almost exclusively localized in astrocytes. We previously reported that cerebral expression of certain genes related to glycogen metabolism changed following instrumental sleep deprivat ...

2010

Implantable Glucose Sensor, IGLUS III – Membrane Technology –

Jürgen Brugger, Nao Takano

In order to realize an implantable glucose sensing system designed within this project, the realization of a selective nanoporous membrane is essential. The final goal of this sub-project is establishing a fabrication process of a semi-permeable membrane c ...

2006

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