Publications related to Coastal cutthroat trout

Intestinal Fish Cell Barrier Model to Assess Transfer of Organic Chemicals in Vitro: An Experimental and Computational Study

Kristin Schirmer, Hannah Inka Schug, Anze Zupanic, Jenny Maner

We studied the role of the fish intestine as a barrier for organic chemicals using the epithelial barrier model built on the rainbow trout (Oncorhynchus mykiss) intestinal cell line, RTgutGC and the newly developed exposure chamber, TransFEr, specifically ...

AMER CHEMICAL SOC2019

Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF

Philippe Renaud, Kristin Schirmer, Carolin Drieschner, Hannah Inka Schug

An in vitro model of the fish intestine is of interest for research and application in diverse fields such as fish physiology, aquaculture and chemical risk assessment. The recently developed epithelial barrier model of the fish intestine relies on the RTg ...

Springer2019

Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro

Philippe Renaud, Kristin Schirmer, Carolin Drieschner

In this study we present the first fish-gut-on-chip model. This model is based on the reconstruction of the intestinal barrier by culturing two intestinal cell lines from rainbow trout, namely epithelial RTgutGC and fibroblastic RTgutF, in an artificial mi ...

2019

TransFEr: a new device to measure the transfer of volatile and hydrophobic organic chemicals across an in vitro intestinal fish cell barrier

Kristin Schirmer, Hannah Inka Schug

Transfer of compounds across cellular barriers is a critical step of compound uptake into organisms. Using in vitro barrier systems to evaluate such transfer is attractive because of the higher throughput and reduced resource needs compared to animal studi ...

ROYAL SOC CHEMISTRY2018

A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC

Kristin Schirmer, Carolin Drieschner, Hannah Inka Schug

The intestine of fish is a multifunctional organ: lined by only a single layer of specialized epithelial cells, it has various physiological roles including nutrient absorption and ion regulation. It moreover comprises an important barrier for environmenta ...

Springer2017

Ultrathin Alumina Membranes as Scaffold for Epithelial Cell Culture from the Intestine of Rainbow Trout

Philippe Renaud, Kristin Schirmer, Songmei Wu, Carolin Drieschner

Permeable membranes are indispensable for in vitro epithelial barrier models. However, currently available polymer-based membranes are low in porosity and relatively thick, resulting in a limited permeability and unrealistic culture conditions. In this stu ...

Amer Chemical Soc2017

Silver nanoparticles inhibit fish gill cell proliferation in protein-free culture medium

Kristin Schirmer, Laura Sigg, Renata Behra, Yang Yue

While short-term exposures of vertebrate cells, such as from fish, can be performed in defined, serum-free media, long-term cultures generally require addition of growth factors and proteins, normally supplied with a serum supplement. However, proteins are ...

Taylor & Francis Ltd2016

A novel two-compartment barrier model for investigating nanoparticle transport in fish intestinal epithelial cells

Kristin Schirmer, Laura Sigg

We introduce a novel in vitro rainbow trout intestinal barrier model and demonstrate its suitability for investigating nanoparticle transport across the intestinal epithelium. Rainbow trout (Oncorhynchus mykiss) intestinal cells (RTgutGC) were grown as mon ...

Royal Soc Chemistry2016

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Coastal cutthroat trout

Intestinal Fish Cell Barrier Model to Assess Transfer of Organic Chemicals in Vitro: An Experimental and Computational Study

Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF

A fish intestinal barrier model to assess the interaction with chemicals in vitro

Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro

TransFEr: a new device to measure the transfer of volatile and hydrophobic organic chemicals across an in vitro intestinal fish cell barrier

What is the role of fish intestine as environment-organism barrier? Mechanistic investigations using fish intestinal cells on a chip

A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC

Ultrathin Alumina Membranes as Scaffold for Epithelial Cell Culture from the Intestine of Rainbow Trout

Silver nanoparticles inhibit fish gill cell proliferation in protein-free culture medium

A novel two-compartment barrier model for investigating nanoparticle transport in fish intestinal epithelial cells

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Chat with Graph Search

A fish intestinal barrier model to assess the interaction with chemicals in vitro

Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro

Intestinal Fish Cell Barrier Model to Assess Transfer of Organic Chemicals in Vitro: An Experimental and Computational Study

TransFEr: a new device to measure the transfer of volatile and hydrophobic organic chemicals across an in vitro intestinal fish cell barrier

What is the role of fish intestine as environment-organism barrier? Mechanistic investigations using fish intestinal cells on a chip

Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF

A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC

Silver nanoparticles inhibit fish gill cell proliferation in protein-free culture medium

A novel two-compartment barrier model for investigating nanoparticle transport in fish intestinal epithelial cells

Ultrathin Alumina Membranes as Scaffold for Epithelial Cell Culture from the Intestine of Rainbow Trout